Estimating the Prevalence of Fetal Alcohol Syndrome
Estimating the Prevalence of Fetal Alcohol Syndrome
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发表时间：
2001
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通讯作者：
Philip A. May;J. Gossage
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作者：
Philip A. May;J. Gossage
自20世纪70年代末以来，许多研究报道了胎儿酒精综合征(FAS)、酒精相关出生缺陷(ARBD)和酒精相关神经发育障碍(ARND)的患病率。这些研究中使用的三种主要研究方法是被动监测、基于临床的研究和主动病例确定。本文描述了这些方法中的每一种，包括它们的优点和缺点，并总结了每种方法产生的Fas的估计流行率。与Fas和其他与酒精相关的异常相关的母亲风险因素包括母亲年龄较高、社会经济地位较低、经常酗酒、有饮酒问题的家人和朋友以及较差的社会和心理指标。总体而言，现有文献指出，在20世纪80年代和90年代，美国每1000名新生儿中就有0.5到2例Fas的患病率。
Since the late 1970s, many studies have reported on the prevalence of fetal alcohol syndrome (FAS), alcohol-related birth defects (ARBD), and alcohol-related neurodevelopmental disorders (ARND). The three main types of research methods used in these studies are passive surveillance, clinic-based studies, and active case ascertainment. This article describes each of these methods, including their strengths and weaknesses, and summarizes the estimated prevalence of FAS produced by each of these approaches. The maternal risk factors associated with FAS and other alcohol-related anomalies include advanced maternal age, low socioeconomic status, frequent binge drinking, family and friends with drinking problems, and poor social and psychological indicators. Overall, the available literature points to a prevalence rate of FAS of 0.5 to 2 cases per 1,000 births in the United States during the 1980s and 1990s.