Finding optimal drug target sites in parasite pathogens.

Finding optimal drug target sites in parasite pathogens.
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寻找寄生虫病原体中的最佳药物靶位点。

DOI:
10.1016/j.pt.2022.12.003
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发表时间:
2023
影响因子:
9.6
通讯作者:
Bogyo,Matthew
Bogyo,Matthew
中科院分区:
医学1区
文献类型:
--
作者:
Bogyo,Matthew

文献摘要

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Benns et al. have recently combined a chemoproteomic profiling method with a CRISPR-based gene-editing method to identify chemically targetable residues essential for fitness in the parasiteToxoplasma gondii. The result is a strategy that enables rapid discovery of new drug targets to combatT. gondiiand other related parasites.