Latent Profile Analyses of Depressive Symptoms in Younger and Older Oncology Patients.
Latent Profile Analyses of Depressive Symptoms in Younger and Older Oncology Patients.
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DOI：
10.1177/1073191118784653
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发表时间：
2020-10
期刊：
影响因子：
3.8
通讯作者：
J Nelson C
中科院分区：
文献类型：
--
作者：
Saracino RM;Cham H;Rosenfeld B;J Nelson C
美国的老龄化将包括老年癌症患者数量的显著增加，其中许多人将经历严重的抑郁症状。虽然老年抑郁症是一个研究得很好的概念，但其在癌症背景下的症状表现尚不清楚。对年轻（40-64岁）和老年（≥65岁）癌症患者（N = 636）的抑郁症状进行了潜在特征分析。样本在临床上是异质的（即，包括所有阶段，以晚期疾病为主）。参与者完成了问卷调查，包括流行病学研究中心抑郁量表，用于潜在的个人资料分析。支持每个年龄组的四级模式。然而，四类模式是显着不同的年轻人和老年人之间的项目平均值在每个相应的潜在类;差异主要是由严重程度，跨类，老年人赞同较轻的症状。关于反向编码项目，发现了一个意想不到的测量问题，这表明它们可能会在流行病学研究中心抑郁量表上为一个重要的患者子集产生不可靠的分数。结果表明，癌症临床医生可以预期看到任何年龄的患者的抑郁症状沿着一个连续的严重程度，老年患者的症状不太严重。
The aging of America will include a significant increase in the number of older patients with cancer, many of whom will experience significant depressive symptoms. Although geriatric depression is a well-studied construct, its symptom presentation in the context of cancer is less clear. Latent profile analysis was conducted on depressive symptoms in younger (40–64 years) and older (≥65 years) patients with cancer (N = 636). The sample was clinically heterogeneous (i.e., included all stages, dominated by advanced stage disease). Participants completed questionnaires including the Center for Epidemiological Studies Depression Scale, which was used for the latent profile analysis. A four-class pattern was supported for each age group. However, the four-class pattern was significantly different between the younger and older groups in terms of the item means within each corresponding latent class; differences were primarily driven by severity such that across classes, older adults endorsed milder symptoms. An unexpected measurement issue was uncovered regarding reverse-coded items, suggesting that they may generate unreliable scores on the Center for Epidemiological Studies Depression Scale for a significant subset of patients. The results indicate that cancer clinicians can expect to see depressive symptoms along a continuum of severity for patients of any age, with less severe symptoms among older patients.
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影响因子：
7.2
作者：
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通讯作者：
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影响因子：
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作者：
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