Severe invasive community-associated methicillin-resistant Staphylococcus aureus infections in previously healthy children
Severe invasive community-associated methicillin-resistant Staphylococcus aureus infections in previously healthy children
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DOI：
10.1097/pcc.0b013e3181988798
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发表时间：
2009-05-01
影响因子：
4.1
通讯作者：
Winkler, Margaret K.
中科院分区：
文献类型：
--
作者：
Creel, Amy M.;Durham, Spencer H.;Winkler, Margaret K.
目的：文献报道了社区相关耐甲氧西林金黄色葡萄球菌（CA-MRSA）感染的增加。大多数严重的、危及生命的感染以前被认为与慢性病或虚弱的患者有关。我们的儿科重症监护病房（PICU）最近发现健康儿童中原发性、严重侵袭性CA-MRSA感染急剧增加。回顾性图表审查所有以前健康的病人承认我们的19床联合内科-外科PICU的主要诊断为严重的侵入性，培养证实CA-MRSA疾病在过去6年。结果：从2006年3月到2007年9月，11名先前健康的患者因严重的原发性侵袭性CA-MRSA感染而入住我们的PICU，相比之下，在过去的5年中没有专利符合这些ID标准。死亡率为27 A，而研究期间PICU的总死亡率为
Objective: An increase in community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections has been reported in the literature. Most severe, life-threatening infections were previously thought to be associated with chronically ill or frail patents. Our pediatric intensive care unit (PICU) has seen a recent dramatic increase in primary, severe invasive CA-MRSA infections in healthy children.Design/Setting. A retrospective chart review of all previously healthy patents admitted to our 19-bed combined medical-surgical PICU with a primary diagnosis of severe invasive, culture-proven CA-MRSA disease during the past 6 years.Results: Eleven previously healthy patients were admitted to our PICU with severe, primary, invasive CA-MRSA infections from March 2006 through September 2007, in contrast to no patents meeting these ID criteria in the preceding 5 years. The mortality rate was 27 A, compared with an overall PICU mortality rate during the study period of