LORIS: a web-based data management system for multi-center studies.
LORIS: a web-based data management system for multi-center studies.
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DOI：
10.3389/fninf.2011.00037
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发表时间：
2011
影响因子：
3.5
通讯作者：
Evans AC
中科院分区：
文献类型：
--
作者：
Das S;Zijdenbos AP;Harlap J;Vins D;Evans AC
纵向在线研究和成像系统 (LORIS) 是一个模块化、可扩展的基于网络的数据管理系统，集成了多中心研究的各个方面：从异构数据采集（成像、临床、行为和遗传学）到存储、处理和最终传播。它提供了一个安全、用户友好且简化的平台，可实现临床试验和复杂的多中心研究流程的自动化。以主题为中心的内部组织允许研究人员捕获并随后从研究队列的任何子集中提取所有纵向或横向信息。广泛的错误检查和质量控制程序、安全性、数据管理、数据查询和管理功能为 LORIS 提供了三重功能（1）持续项目协调和数据采集监控（2）数据存储/清理/查询，（3）与任意外部数据处理“管道”的接口。 LORIS 是一个完整的解决方案，已经过多中心纵向项目 10 年完整生命周期的彻底测试，目前正在支持众多国际神经发育和神经退行性疾病研究项目。
Longitudinal Online Research and Imaging System (LORIS) is a modular and extensible web-based data management system that integrates all aspects of a multi-center study: from heterogeneous data acquisition (imaging, clinical, behavior, and genetics) to storage, processing, and ultimately dissemination. It provides a secure, user-friendly, and streamlined platform to automate the flow of clinical trials and complex multi-center studies. A subject-centric internal organization allows researchers to capture and subsequently extract all information, longitudinal or cross-sectional, from any subset of the study cohort. Extensive error-checking and quality control procedures, security, data management, data querying, and administrative functions provide LORIS with a triple capability (1) continuous project coordination and monitoring of data acquisition (2) data storage/cleaning/querying, (3) interface with arbitrary external data processing “pipelines.” LORIS is a complete solution that has been thoroughly tested through a full 10 year life cycle of a multi-center longitudinal project1 and is now supporting numerous international neurodevelopment and neurodegeneration research projects.