Dual echo positive contrast bSSFP for real-time visualization of passive devices during magnetic resonance guided cardiovascular catheterization.
Dual echo positive contrast bSSFP for real-time visualization of passive devices during magnetic resonance guided cardiovascular catheterization.
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DOI：
10.1186/s12968-014-0088-7
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发表时间：
2014-10-28
期刊：
影响因子：
--
通讯作者：
Faranesh AZ
中科院分区：
文献类型：
--
作者：
Campbell-Washburn AE;Rogers T;Xue H;Hansen MS;Lederman RJ;Faranesh AZ
心血管磁共振(CMR)引导的心血管插管可能会减少电离辐射暴露，并使新的干预成为可能。商业上可用的顺磁X射线设备在CMR图像中产生一个小的信号空洞，这是模棱两可的，不足以指导插管过程。这项工作旨在通过开发实时正对比度序列来提高现有X射线设备的实时CMR，该序列将设备的颜色覆盖到解剖结构上。使用双回波bSSFP序列来同时产生反相正对比度图像和bSSFP图像。采用了一种可变翻转角度的方案来降低比吸收率(SAR)，从而降低了器件发热。使用图像处理将设备从背景信号中分离出来，并将设备的颜色覆盖在解剖结构上，模拟活动设备的可视化。概念验证实验是使用商业上可买到的镍镍导丝在约克郡猪的左心导管术中进行的。双回波脉冲序列产生的时间分辨率为175ms(5.7帧/秒)，GRAPPA加速因子为4。图像处理被实时执行，设备在解剖上的彩色覆盖被显示给操作员，而没有延迟。在左心导管术中，彩色覆盖层准确地描绘了导丝的位置，背景污染最小。在CMR引导的心血管插管过程中，能够有效地可视化商业上可用的X射线设备，结合安全的低SAR脉冲序列，可能会加速介入性CMR的临床翻译。本文的在线版本(doi：10.1186/s12968-0140088-7)包含补充材料，授权用户可以使用。
Cardiovascular magnetic resonance (CMR) guided cardiovascular catheterizations can potentially reduce ionizing radiation exposure and enable new interventions. Commercially available paramagnetic X-Ray devices create a small signal void in CMR images, which is ambiguous and insufficient to guide catheterization procedures. This work aims to improve real-time CMR of off-the-shelf X-Ray devices by developing a real-time positive contrast sequence with color overlay of the device onto anatomy. A dual-echo bSSFP sequence was used to generate both a dephased positive contrast image and bSSFP image simultaneously. A variable flip angle scheme was implemented to reduce the specific absorption rate (SAR) and hence device heating. Image processing was used to isolate the device from background signal, and the device was overlaid in color on the anatomy, mimicking active device visualization. Proof-of-concept experiments were performed using a commercially available nitinol guidewire for left heart catheterization in Yorkshire swine. The dual echo pulse sequence generated a temporal resolution of 175 ms (5.7 frames/second) with GRAPPA acceleration factor 4. Image processing was performed in real-time and color overlay of the device on the anatomy was displayed to the operator with no latency. The color overlay accurately depicted the guidewire location, with minimal background contamination, during left heart catheterization. The ability to effectively visualize commercially available X-Ray devices during CMR-guided cardiovascular catheterizations, combined with safe low-SAR pulse sequences, could potentially expedite the clinical translation of interventional CMR. The online version of this article (doi:10.1186/s12968-014-0088-7) contains supplementary material, which is available to authorized users.
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影响因子：
3.5
作者：
Koktzoglou, Ioannis;Li, Debiao;Dharmakumar, Rohan
通讯作者：
Dharmakumar, Rohan
DOI：
10.1186/1532-429x-14-38
发表时间：
2012-06-21
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Sonmez M;Saikus CE;Bell JA;Franson DN;Halabi M;Faranesh AZ;Ozturk C;Lederman RJ;Kocaturk O
通讯作者：
Kocaturk O
影响因子：
3.3
作者：
George, Ashvin K.;Derbyshire, J. Andrew;Faranesh, Anthony Z.
通讯作者：
Faranesh, Anthony Z.
影响因子：
4.8
作者：
McVeigh, ER;Guttman, MA;Lederman, RJ
通讯作者：
Lederman, RJ
影响因子：
2.5
作者：
Paul, Dominik;Zaitsev, Maxim
通讯作者：
Zaitsev, Maxim