Estimating the probability of positive crossmatch after negative virtual crossmatch

Estimating the probability of positive crossmatch after negative virtual crossmatch
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发表时间:
2012-12
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通讯作者:
Kristiaan M. Glorie
Kristiaan M. Glorie
中科院分区:
其他
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作者:
Kristiaan M. Glorie

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本文对肾交换配型中虚拟交叉匹配失败的概率进行了估计。具体地说,在负虚拟交叉匹配后,正交叉匹配的概率与接受者的PRA水平有关。使用荷兰的肾脏交换数据,我们发现了重要的证据表明,这种可能性随着PRA水平的非线性增加。我们估计了一个描述这种关系的概率模型。
This paper estimates the probability of virtual crossmatch failure in kidney exchange matching. In particu-lar, the probability of a positive crossmatch after a negative virtual crossmatch is related to the recipient’s PRA level. Using Dutch kidney exchange data, we find significant evidence that this probability increases non-linearly with PRA level. We estimate a probit model that describes this relationship.