Removal of Plaque and Stent Artifacts in Subtraction CT Angiography Using Nonrigid Registration and a Volume Penalty
Removal of Plaque and Stent Artifacts in Subtraction CT Angiography Using Nonrigid Registration and a Volume Penalty
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使用非刚性配准和体积惩罚去除减影 CT 血管造影中的斑块和支架伪影
DOI：
10.1109/iembs.2005.1615414
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
P. Suetens
中科院分区：
文献类型：
--
作者：
D. Loeckx;S. Drisis;F. Maes;D. Vandermeulen;G. Marchal;P. Suetens
计算机断层扫描血管造影术（CTA）是血管成像的既定工具。然而，对比图像中的高强度结构会严重妨碍管腔可视化。这可以通过减影CTA来解决，其中从对比图像中减去原生图像。然而，病人和器官的运动限制了这项技术的应用。本文提出了一种用于减影CT血管造影的全自动基于强度的非刚性3D配准算法，使用惩罚项来避免配准过程中的体积变化。对四个临床数据集的视觉和自动验证清楚地表明，该算法大大减少了减影CTA中的运动伪影。大多数伪影消失，支架或钙化斑块的最小位移引起的伪影也消失，允许血管腔的2D和3D无伪影可视化。这使得整个血管结构的快速概览成为可能，并为较小血管的可视化开辟了可能性
Computed tomography angiography (CTA) is an established tool for vascular imaging. However, high-intense structures in the contrast image can seriously hamper luminal visualisation. This can be solved by subtraction CTA, where a native image is subtracted from the contrast image. However, patient and organ motion limit the application of this technique. Within this paper, a fully automated intensity-based nonrigid 3D registration algorithm for subtraction CT angiography is presented, using a penalty term to avoid volume change during registration. Visual and automated validation on four clinical datasets clearly show that the algorithm strongly reduces motion artifacts in subtraction CTA. Most artifacts disappear, also artifacts caused by minimal displacement of stents or calcified plaques, allowing a 2D and 3D artifact-free visualisation of the vessel lumen. This enables a quick overview of the whole vascular structure and opens the possibility to the visualisation of smaller vessels