The Contribution of Life Course Determinants to Early Childhood Caries: A 2-Year Cohort Study
The Contribution of Life Course Determinants to Early Childhood Caries: A 2-Year Cohort Study
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生命历程决定因素对儿童早期龋齿的影响：一项为期 2 年的队列研究
DOI：
10.1159/000335574
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发表时间：
2012-01-01
期刊：
影响因子：
4.2
通讯作者：
Lin, H. C.
中科院分区：
文献类型：
--
作者：
Zhou, Y.;Yang, J. Y.;Lin, H. C.
背景：幼儿龋齿（ECC）在中国是一个严重的问题。关于3岁以下儿童发生ECC的危险因素的数据很少。在这项研究中，我们调查了一组8个月大的儿童生命过程中发生ECC的危险因素。方法：从中国南方广州市的一个农村社区招募225名8个月大的儿童。在基线和每6个月收集一次信息。调查问卷的目的是收集社会经济和行为信息。用表面法记录龋病，用可见菌斑指数评估口腔卫生。利用微生物学试验确定牙菌斑中是否存在变形链球菌（S. mutans）。计算ECC的发病密度，并进行广义估计方程分析，识别危险因素。结果：8 ~ 14月龄、14 ~ 20月龄、20 ~ 26月龄和26 ~ 32月龄儿童的发病率密度分别为0、0.02 +/- 0.19、0.05 +/- 0.26和0.20 +/- 0.59（面/100面月）。多变量分析显示，母亲受教育程度低、家庭月收入高、牙釉质发育不全、身高低于平均水平、可见菌斑比例高、存在腮腺炎链球菌是儿童发生ECC的危险预测因素。结论：社会经济、行为和生物因素与ECC之间存在一定的关系。早期生活因素在ECC的发展中起着重要作用。版权所有(c) 2012 S. Karger AG，巴塞尔
Background: Early childhood caries (ECC) is a serious problem in China. There are few data available on the risk factors contributing to ECC in children under the age of 3 years. In this study we investigate the risk factors for ECC in the life course of a cohort of 8-month-old children. Methods: A total of 225 children aged 8 months were recruited from a rural community in the city of Guangzhou in southern China. Information was collected at baseline and once every 6 months. The questionnaire was designed to collect socioeconomic and behavioural information. Dental caries was recorded by surface and oral hygiene was assessed using the visible plaque index. The presence of Streptococcus mutans (S. mutans) in dental plaque was determined using microbiological tests. The incidence density of ECC was calculated and generalised estimating equation analysis was performed to identify the risk factors. Results: The incidence density among 8 to 14-, 14 to 20-, 20 to 26- and 26 to 32-month-old children was found to be 0, 0.02 +/- 0.19, 0.05 +/- 0.26 and 0.20 +/- 0.59 (surfaces/100 surface-months), respectively. Multivariable analysis showed that mothers who had a low level of education, families with higher monthly income, enamel hypoplasia of the teeth, lower than average height, a high proportion of visible plaque, and the presence of S. mumps were risk predictors for ECC of the children. Conclusions: There appears to be a relationship between socioeconomic, behavioural and biological factors and ECC. Early life factors play an important role in the development of ECC. Copyright (c) 2012 S. Karger AG, Basel