RABIES TRANSMISSION BY NONBITE ROUTE
RABIES TRANSMISSION BY NONBITE ROUTE
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DOI：
10.2307/4591470
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发表时间：
1962-01-01
影响因子：
3.3
通讯作者：
CONSTANTINE, DG
中科院分区：
文献类型：
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作者：
CONSTANTINE, DG
为了验证两名死于狂犬病的人在访问德克萨斯州尤瓦尔迪附近蝙蝠出没的弗里奥洞穴期间通过非咬伤途径感染狂犬病的怀疑，将各种本地食肉动物（狐狸、浣熊、负鼠、郊狼、环尾、臭鼬）以及家养狗和猫关在洞里的笼子里。十二只狐狸和十只土狼，其中一些被关在防蝙蝠和防节肢动物的笼子里，在洞穴中呆了 24 至 30 天后死于狂犬病。通过血清中和试验分离并鉴定病毒。潜伏期为28至109天。在 1961 年实验之前，除了两只动物外，所有动物都已被隔离至少 6 个月。研究结果支持将气溶胶等空气传播介质视为狂犬病的传播机制。
To test suspicions that 2 persons who died of rabies had been infected via a nonbite route during visits to bat-infested Frio Cave near Uvalde, Tex., various native carnivores (foxes, raccoons, opossums, coyotes, ringtails, skunks) and domestic dogs and cats were kept in cages in the cavern. Twelve foxes and ten coyotes, including some kept in bat-proof and arthropod-proof cages, died of rabies after periods of from 24 to 30 days in the caves. Virus was isolated and identified by the serum neutralization test. Incubation periods ranged from 28 to 109 days. All but 2 of the animals had been kept in isolation at least 6 months prior to the 1961 experiment. The findings support consideration of an airborne medium, such as an aerosol, as the mechanism of transmission of rabies.