Hybrid odontogenic tumor of calcifying odontogenic cyst and ameloblastic fibroma
Hybrid odontogenic tumor of calcifying odontogenic cyst and ameloblastic fibroma
复制标题
DOI：
10.1016/j.tripleo.2004.01.003
复制
发表时间：
2004-07-01
期刊：
影响因子：
--
通讯作者：
Kim, J
中科院分区：
文献类型：
--
作者：
Yoon, JH;Kim, HJ;Kim, J
由两种不同类型的病变组成的牙源性肿瘤是罕见的。我们报告一位22岁的韩国女性，其右后上颌骨发生牙源性肿瘤，由牙源性钙化囊肿及造釉细胞纤维瘤组成。肿瘤有一个囊性成分，有成釉细胞上皮衬里和所谓的鬼细胞聚集，在囊肿附近有牙本质样物质沉积。这些都是牙源性钙化囊肿的特征。在囊壁的牙乳头样间质内观察到釉质器官样上皮岛。此外，肿瘤的实体部分具有成釉细胞纤维瘤的特征，即，粘液样细胞基质，具有许多细长的成釉细胞上皮岛。在造釉细胞纤维瘤区域也发现了鬼细胞团。影细胞的分布表明这是一个混合病变而不是碰撞肿瘤。
Odontogenic tumors composed of 2 distinct types of lesions are unusual. We report an odontogenic tumor that was composed of calcifying odontogenic cyst and ameloblastic fibroma that occurred in the right posterior maxilla of a 22-year-old Korean woman. The tumor had a cystic component with an ameloblastic epithelial lining and conglomerates of so-called ghost cells, and there were deposits of dentinoid material adjacent to the cyst. These are features characteristic of calcifying odontogenic cyst. Enamel organ-like epithelial islands were observed within a dental papilla-like stroma of the cyst wall. Additionally, a solid portion of the tumor had characteristic features of ameloblastic fibroma, i.e., a myxoid cellular stroma with numerous elongated islands of ameloblastic epithelium. Ghost cell masses were found in the area of ameloblastic fibroma as well. The distribution of the ghost cells suggests that this is a hybrid lesion rather than a collision tumor.