Responding to a 100-Year-Old Challenge from Fisher: A Biometrical Analysis of Adult Height in the NLSY Data Using Only Cousin Pairs.
Responding to a 100-Year-Old Challenge from Fisher: A Biometrical Analysis of Adult Height in the NLSY Data Using Only Cousin Pairs.
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回应费舍尔 100 年前的挑战:仅使用表兄弟对 NLSY 数据中成人身高的生物特征分析。
DOI:
10.1007/s10519-019-09967-6
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发表时间:
2019
影响因子:
2.6
通讯作者:
vandenOord,EdwinJCG
中科院分区:
文献类型:
--
作者:
Rodgers,JosephLee;Garrison,SMason;O'Keefe,Patrick;Bard,DavidE;Hunter,MichaelD;Beasley,WilliamH;vandenOord,EdwinJCG
In 1918, Fisher suggested that his research team had consistently found inflated cousin correlations. He also commented that because a cousin sample with minimal selection bias was not available the cause of the inflation could not be addressed, leaving this inflation as a challenge still to be solved. In the National Longitudinal Survey of Youth (the NLSY79, the NLSY97, and the NLSY-Children/Young Adult datasets), there are thousands of available cousin pairs. Those in the NLSYC/YA are obtained approximately without selection. In this paper, we address Fisher’s challenge using these data. Further, we also evaluate the possibility of fitting ACE models using only cousin pairs, including full cousins, half-cousins, and quarter-cousins. To have any chance at success in such a restricted kinship domain requires an available and highly-reliable phenotype; we use adult height in our analysis. Results provide a possible answer to Fisher’s challenge, and demonstrate the potential for using cousin pairs in a stand-alone analysis (as well as in combination with other biometrical designs).
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影响因子:
4.8
作者:
J. Peterson;R. Ebel;D. O'Keeffe;T. Matsubara;R. Estabrook
通讯作者:
R. Estabrook
DOI:
--
发表时间:
1983
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
RoomeJr,PW;Philley,JC;Peterson,JA
通讯作者:
Peterson,JA
DOI:
10.1016/s0021-9258(17)47229-2
发表时间:
1984-07
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
C. Batie;Henry KaminS
通讯作者:
C. Batie;Henry KaminS
DOI:
--
发表时间:
1981
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Batie,CJ;Kamin,H
通讯作者:
Kamin,H
影响因子:
15
作者:
L. Fieser
通讯作者:
L. Fieser