IMMUNODEFENCE OF THE INNER-EAR - LYMPHOCYTE-MACROPHAGE INTERACTION IN THE ENDOLYMPHATIC SAC
IMMUNODEFENCE OF THE INNER-EAR - LYMPHOCYTE-MACROPHAGE INTERACTION IN THE ENDOLYMPHATIC SAC
复制标题
DOI：
10.3109/00016488009127140
复制
发表时间：
1980-01-01
影响因子：
1.4
通讯作者：
STAHLE, J
中科院分区：
文献类型：
--
作者：
RASKANDERSEN, H;STAHLE, J
由于靠近感染区域，[豚鼠]内耳的感觉器官可能依赖于有效的抗菌防御。在这种情况下，内淋巴向内淋巴囊的纵向流动可能非常重要。进入耳朵的物质可以自动被携带到内淋巴管的远端，那里有淋巴细胞，并发生内淋巴吞噬作用。在囊上皮的中间部分，存在标记进入物质的形态标志。可以看到淋巴细胞和巨噬细胞之间的剧烈相互作用，类似于在抗原激活的淋巴组织中观察到的相互作用。囊被丰富的毛细淋巴管和血管网络包围。
Owing to their proximity to areas exposed to infection, the sensory organs of the [guinea pig] inner ear are probably dependent on an efficient antimicrobial defense. The longitudinal flow of endolymph to the endolymphatic sac may be of major importance in this context. Substances entering the ear can be automatically carried to the distal part of the endolymphatic duct where lymphoid cells are present and endolymphatic phagocytosis occurs. In the intermediate part of the epithelium of the sac, morphological signs marking the incoming substances are present. A vigorous interaction between lymphocytes and macrophages, similar to that observed in antigen-activated lymphoid tissue, may be seen. The sac is here surrounded by a rich network of lymphatic capillaries and blood vessels.