Effect of probe contact pressure on the photoplethysmographic assessment of conduit artery stiffness
Effect of probe contact pressure on the photoplethysmographic assessment of conduit artery stiffness
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DOI：
10.1117/1.jbo.18.2.027004
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发表时间：
2013-02-01
影响因子：
3.5
通讯作者：
Kviesis-Kipge, Edgars
中科院分区：
文献类型：
--
作者：
Grabovskis, Andris;Marcinkevics, Zbignevs;Kviesis-Kipge, Edgars
目前，光电体积描记术（PPG）是生物光子和生物医学研究人员经常研究的光学血液脉动检测技术，因为它显示出估计动脉硬度（AS）的高潜力。诊断有用信息的提取需要具有良好重复性的标准化测量程序。然而，一个至关重要的因素-探头的最佳接触压力（CP）的影响往往被忽略。此外，没有报告CP值来评估这些影响。假设在非最佳探头CP下记录时，根据PPG脉搏波二阶导数参数B/a估计的AS非常不一致。我们的初步研究证实了这一点，在体内PPG记录从管道动脉网站在可变探头CP（0至15 kPa）的5名健康受试者，通过使用880 nm反射型传感器，力传感器，PPG交流（AC）信号脉冲面积得出的最佳CP标准。根据具有可变CP的PPG计算的B/a值显示变化> 300%。相反，在最佳CP下，B/a表现出高重复性（变异系数
Currently, photoplethysmography (PPG) is a frequently studied optical blood pulsation detection technique among biophotonic and biomedical researchers due to the fact that it shows high potential for estimating the arterial stiffness (AS). The extraction of diagnostically useful information requires standardized measurement procedure with good repeatability. However, the effects of a crucially important factor-the optimal contact pressure (CP) of the probe-are often ignored. Also, CP values are not reported to evaluate those effects. It is hypothesized that AS estimated from PPG pulse wave 2nd derivative parameter b/a is strongly inconsistent when recorded at nonoptimal probe CP. Our pilot study confirmed this during in vivo PPG recordings from conduit artery sites on five healthy subjects at variable probe CP (0 to 15 kPa) by using 880 nm reflectance type sensor, force transducer, and PPG alternating current (AC) signal pulse area derived optimal CP criterion. The b/a values, calculated from PPG with variable CP, showed variation >300 percent. In contrast, at the optimal CP, the b/a showed high repeatability (coefficient of variability