Possible role for cathepsins B and L in bacteriolysis by Japanese eel skin

Possible role for cathepsins B and L in bacteriolysis by Japanese eel skin
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DOI:
10.1006/fsim.1998.0160
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发表时间:
1999-01-01
影响因子:
4.7
通讯作者:
Aranishi, F
Aranishi, F
中科院分区:
农林科学2区
文献类型:
--
作者:
Aranishi, F

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用冻干溶壁微球菌(Micrococcus lysodeikticus)和鳗利斯特氏菌(Listonella anguillarum)测定了日本鳗鲡(Anguilla japonica)皮肤提取物的溶菌活性,并与组织蛋白酶(cathepsin)B和L活性进行了相关分析。结果表明,至少在酸性条件下,两种或两种组织蛋白酶都与革兰氏阴性菌的防御溶菌作用有关,是A.日本南瓜。
Bacteriolytic activity of skin extracts ofAnguilla japonicawere measured using lyophilizedMicrococcus lysodeikticusorListonella anguillarumand correlated with cathepsin B and L activities. The results indicate that, at least under acid conditions, both or either of the cathepsins are associated with defence bacteriolysis of Gram-negative bacteria and are a part of nonspecific immunity ofA. japonicaskin.