Tools for comparative protein structure modeling and analysis
Tools for comparative protein structure modeling and analysis
复制标题
DOI：
10.1093/nar/gkg543
复制
发表时间：
2003-07-01
影响因子：
14.9
通讯作者：
Sali, A
中科院分区：
文献类型：
--
作者：
Eswar, N;John, B;Sali, A
描述了以下用于比较蛋白质结构建模和分析的资源（http：salilab.org）：MODELLER，一个通过满足空间约束进行比较建模的程序; MODWEB，一个依赖PSI-BLAST、IMPALA和MODELLER进行自动比较建模的网络服务器; MODLOOP，一个依赖MODELLER进行自动环路建模的网络服务器; MOULDER，MODWEB的一个CPU密集型协议，用于基于遥远的已知结构构建比较模型; MODBASE，与已知结构可检测相关的所有序列的注释比较模型的综合数据库; MODVIEW，用于Linux的Netscape插件，其集成了多个序列和结构的查看;和SNPWEB，用于基于结构预测单个氨基酸取代的功能影响的网络服务器。
The following resources for comparative protein structure modeling and analysis are described (http://salilab.org): MODELLER, a program for comparative modeling by satisfaction of spatial restraints; MODWEB, a web server for automated comparative modeling that relies on PSI-BLAST, IMPALA and MODELLER; MODLOOP, a web server for automated loop modeling that relies on MODELLER; MOULDER, a CPU intensive protocol of MODWEB for building comparative models based on distant known structures; MODBASE, a comprehensive database of annotated comparative models for all sequences detectably related to a known structure; MODVIEW, a Netscape plugin for Linux that integrates viewing of multiple sequences and structures; and SNPWEB, a web server for structure-based prediction of the functional impact of a single amino acid substitution.