Risk factors for the onset of panic disorder and other panic attacks in a prospective, population-based study.
Risk factors for the onset of panic disorder and other panic attacks in a prospective, population-based study.
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一项基于人群的前瞻性研究中惊恐障碍和其他惊恐发作的危险因素。
DOI：
10.1093/oxfordjournals.aje.a115499
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发表时间：
1990
影响因子：
5
通讯作者：
Eaton,WW
中科院分区：
文献类型：
--
作者：
Keyl,PM;Eaton,WW
在1980-1983年的不同12个月期间，在12823名流行病学集水区计划的参与者中，总共发现了38.3起恐慌性发作事件。将这些没有恐怖刺激的病例与766名对照组进行比较。对恐慌症发作的风险因素进行了研究，将其归类为恐慌症、严重和不明原因的恐慌症发作或其他恐慌症发作。对于有心血管症状的发作和有心理症状的发作，危险因素也进行了检查。在每种类型的攻击中，女性比男性面临更大的风险(相对几率在1.36到2.25之间)。65岁或65岁以上的人比年轻人的风险更低(与30岁至44岁的人相比，相对优势从0.26到0.71)。心脏症状、呼吸急促、抑郁或重大悲伤发作、药物滥用或依赖、酗酒或依赖以及癫痫发作的病史都与恐慌症发作密切相关。心脏症状史与心血管症状发作的相关性比与心理症状发作的相关性更强(相对优势比8.36比2.23)。癫痫史与有心理症状的发作比与有心血管症状的发作有更强的相关性(相对优势比5.21比1.58)。
A total of 38.3 cases of incident panic attack were identified among 12,823 participants in the Epidemiologic Catchment Area Program over various 12-month periods in 1980–1983. These cases not phobia-stimulated were compared with 766 controls. Risk factors were examined for the onset of panic attacks, with attacks categorized as panic disorder, severe and unexplained panic attacks, or other panic attacks. Risk factors were also examined for the onset of attacks in which cardiovascular symptoms were experienced and those in which psychologic symptoms were experienced. Females were at greater risk than males for each category of attacks (relative odds ranged from 1.36 to 2.25). Persons aged 65 years or older were at lower risk than younger persons (relative odds, compared with 30- to 44-year-olds, ranged from 0.26 to 0.71). A history of cardiac symptoms, shortness of breath, depression or a major grief episode, drug abuse or dependence, alcohol abuse or dependence, and seizures were each strongly associated with panic attacks. A history of cardiac symptoms was more strongly associated with attacks in which cardiovascular symptoms were experienced than with attacks in which psychologic symptoms were experienced (relative odds, 8.36 vs. 2.23). A history of seizures was more strongly associated with attacks with psychologic symptoms than with attacks with cardiovascular symptoms (relative odds, 5.21 vs. 1.58).