Synthesis and turnover of sulfogalactoglycerolipid, a membrane lipid, during spermatogenesis.
Synthesis and turnover of sulfogalactoglycerolipid, a membrane lipid, during spermatogenesis.
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精子发生过程中磺基半乳糖甘油脂（一种膜脂）的合成和周转。
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
M. Kornblatt
中科院分区：
文献类型：
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作者：
M. Kornblatt
用35S标记磺胺半乳糖甘油脂（SGG），研究了SGG的合成和转化。随着时间的推移，观察睾丸[35S]SGG的丢失及其在输精管和附睾的出现。用[3H]胸腺嘧啶标记DNA，比较两种同位素的行为。结果表明，SGG仅发生在非常早期的精母细胞中，而且一旦形成，该化合物就不会翻转。当生殖细胞死亡或成熟为精子时，SGG就会从睾丸中消失。
The synthesis and turnover of sulfogalactoglycerolipid (SGG) were studied by in vivo labelling of SGG with 35S. The loss of [35S]SGG from the testes and its appearance in the vas deferens plus epididymis were followed with time. DNA was labelled by administration of [3H]thymidine and the behavior of the two isotopes was compared. The results demonstrate that SGG snythesis occurs only in very early spermatocytes and that, once made, the compound does not turn over. The SGG is lost from the testes when germinal cells die or mature into spermatozoa.