Body mass index and chronic airflow limitation in a worldwide population-based study
Body mass index and chronic airflow limitation in a worldwide population-based study
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DOI：
10.1177/1479972315626012
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发表时间：
2016-05-01
影响因子：
4.1
通讯作者：
Franssen, Frits M. E.
中科院分区：
文献类型：
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作者：
Vanfleteren, Lowie E. G. W.;Lamprecht, Bernd;Franssen, Frits M. E.
营养状况与慢性气流受限（CAL）的临床结局相关，但流行病学研究很少。我们的目的是评估身体质量指数（BMI）和CAL之间的关系，考虑到混杂因素。纳入了来自23个国家26个研究中心的18，606名BOLD倡议参与者（49%男性，21%吸烟者，平均年龄：55.8 ± 11.2岁，平均BMI：26.7 ± 5.5 kg/m2）。CAL定义为使用支气管扩张剂后第1秒用力呼气量/用力肺活量<正常值下限。低BMI和肥胖BMI定义为：
Nutritional status has been associated with clinical outcome in chronic airflow limitation (CAL), but epidemiological studies are scarce. We aimed to assess the relationship between body mass index (BMI) and CAL, taking into account confounding factors. 18,606 participants (49% male, 21% smokers, mean age: 55.8 +/- 11.2 years, mean BMI: 26.7 +/- 5.5 kg/m(2)) of the BOLD initiative from 26 sites in 23 countries were included. CAL was defined as post-bronchodilator forced expiratory volume in the first second/forced vital capacity < lower limit of normal. Low and obese BMI were defined as