Atherogenic Dyslipidemia and Residual Vascular Risk After Stroke or Transient Ischemic Attack
Atherogenic Dyslipidemia and Residual Vascular Risk After Stroke or Transient Ischemic Attack
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DOI：
10.1161/strokeaha.121.034593
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发表时间：
2022-01-01
期刊：
影响因子：
8.3
通讯作者：
Kitagawa, Kazuo
中科院分区：
文献类型：
--
作者：
Hoshino, Takao;Ishizuka, Kentaro;Kitagawa, Kazuo
背景和目的：尽管目前的指南为基础的管理，中风患者保留了进一步血管事件的重大风险。我们的目的是评估动脉粥样硬化血脂异常（AD）的贡献，这是一个前瞻性的观察性研究，其中792例（平均年龄70.1岁，男性，60.2%）急性缺血性中风（n=710）或短暂性脑缺血发作（n=82）在发病1周内连续入组，并随访1年。AD定义为甘油三酯水平升高>= 150 mg/dL和HDL-C（高密度脂蛋白胆固醇）水平降低
BACKGROUND AND PURPOSE: Notwithstanding the current guideline-based management, patients with stroke retain a substantial risk of further vascular events. We aimed to assess the contribution of atherogenic dyslipidemia (AD) to this residual risk.METHODS: This was a prospective observational study, in which 792 patients (mean age, 70.1 years; male, 60.2%) with acute ischemic stroke (n=710) or transient ischemic attack (n=82) within 1 week of onset were consecutively enrolled and followed for 1 year. AD was defined as having both elevated levels of triglycerides >= 150 mg/dL and low HDL-C (high-density lipoprotein cholesterol)