Do older adults with knee osteoarthritis place greater loads on the knee during gait? A preliminary study
Do older adults with knee osteoarthritis place greater loads on the knee during gait? A preliminary study
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DOI：
10.1016/j.apmr.2004.05.015
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发表时间：
2005-04-01
影响因子：
4.3
通讯作者：
Marsh, AP
中科院分区：
文献类型：
--
作者：
Messier, SP;DeVita, P;Marsh, AP
目的：比较膝关节骨关节炎（OA）老年人与所有年龄、性别和体重匹配的健康队列的步态，以提供初步数据来检验膝关节OA成年人膝关节力矩异常的假设，并与健康成年人相比，在行走过程中膝关节承受更大的负荷。设计：健康和骨关节炎老年人的非随机描述性研究。大学临床研究实验室。参与者：10名有胫股和/或髌股放射学证据以及膝关节OA所致疼痛和残疾的老年人和10名年龄、性别和体重匹配的健康成年人。干预措施：不适用。主要结局指标：三维步态分析，计算膝关节力和髋、膝、踝关节力矩;协方差分析，调整组间步行速度差异;结果：OA组和健康组的关节力和力矩在统计学上没有差异。OA组相对于健康组的非显著性差异包括膝关节压缩性增加7%至8%。（OA组，3.67 +/- 0.24体重[BW];健康组，3.40 +/- 0.24 BW）和剪切（OA组，0.47 +/- 0.04 BW;健康组，0.44 +/-0.04 BW）力，膝关节伸展力矩增加33%（OA组，0.32 +/- .07Nm/kg;健康组，0.24 +/- .07Nm/kg），24%的下膝内展力矩（OA组，.25 +/- .06Nm/kg;，健康组，.33 +/- .06Nm/kg）结论：以前的研究表明机械负荷可能与膝关节OA有关。我们的研究结果没有提供统计学证据来支持这一假设。尽管如此。数据的趋势，沿着先前的结果，表明需要进一步研究膝关节OA的生物力学途径的可能存在。
Objective: To compare the gait of older adults with knee osteoarthritis (OA) to all age-, sex-, and weight-matched healthy cohort that would provide preliminary data to examine the hypothesis that adults with knee OA have abnormal knee joint moments and place greater loads on the knee joint during walking compared with healthy adults.Design: Nonrandomized, descriptive study of healthy and osteoarthritic older adults.Setting: University clinical research laboratory.Participants: Ten older adults with tibiofemoral and/or patellofemoral radiographic evidence and pain and disability attributed to knee OA and 10 age-, sex-, and weight-matched healthy adults.Interventions: Not applicable.Main Outcome Measures: Three-dimensional gait analysis to calculate knee joint forces and hip, knee, and ankle joint moments; an analysis of covariance adjusted for differences in walking speed between the groups; electromyocgraphic data to verify our interpretation of the knee joint moment data.Results: The joint forces and moments did not differ statistically between the OA and healthy groups. Nonsignificant differences in the OA group relative to the healthy group included between 7% and 8% greater knee joint compressive (OA group, 3.67 +/- 0.24 body weight [BW]; healthy group, 3.40 +/- 0.24 BW) and shear (OA group, 0.47 +/- 0.04 BW; healthy group, .44 +/- .04 BW) forces, 33% higher knee extension moments (OA group, .32 +/- .07Nm/kg; healthy group, .24 +/- .07Nm/kg), and 24% lower knee internal abduction moments (OA group, .25 +/- .06Nm/kg;, healthy group, .33 +/- .06Nm/kg).Conclusions: Previous research suggests that mechanical overload may be associated with knee OA. Our results do not provide statistical evidence to Support this hypothesis. Nevertheless. the trends in the data, along with previous results, Suggest the need to investigate further the possible existence of a biomechanical pathway to knee OA.