High-speed observation of cavitation bubble clouds near a tissue boundary in high-intensity focused ultrasound fields
High-speed observation of cavitation bubble clouds near a tissue boundary in high-intensity focused ultrasound fields
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DOI：
10.1016/j.ultras.2008.09.010
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发表时间：
2009-03-01
期刊：
影响因子：
4.2
通讯作者：
Wang, Supin
中科院分区：
文献类型：
--
作者：
Chen, Hong;Li, Xiaojing;Wang, Supin
利用高速摄影技术研究了高强度聚焦超声（HIFU）在组织边界附近产生的空化气泡云。在最初的100 ms的连续HIFU曝光期间，总共捕获了171个图像系列，这表明在组织边界处的空化气泡云组织成两种结构-“锥形气泡云结构”记录在146个图像系列中，“冠状气泡云结构”记录在18个图像系列中。其余7个图像系列显示了这两种结构的互换。结果表明，空化泡在组织边界处首先出现，然后发展为锥形泡云。锥形气泡云结构的特征在于在组织边界的前方具有几乎固定的尖端。当空化气泡最初出现远离组织边界时，它们演变成冠状气泡云。所有记录的图像序列均显示组织边界变形。(C)2008年由Elsevier B. V.出版。
Cavitation bubble clouds generated near a tissue boundary by high-intensity focused ultrasound (HIFU) were studied using high-speed photography. In all, 171 image series were captured during the initial 100 ms of continuous HIFU exposure, which showed that cavitation bubble clouds at the tissue boundary organized into two structures - "cone-shape bubble cloud structure" recorded in 146 image series and "crown-shape bubble cloud structure" recorded in 18 image series. The remaining 7 image series showed the interchanging of these two structures. It was found that when cavitation bubbles first appeared at the tissue boundary, they developed to cone-shape bubble cloud. The cone-shape bubble cloud structure was characterized by a nearly fixed tip in front of the tissue boundary. When the cavitation bubbles initially appeared away from the tissue boundary they evolved into a crown-shape bubble cloud. Deformation of tissue boundary was shown in all the recorded image series. (C) 2008 Published by Elsevier B.V.