Associated factors and health impact of sarcopenia in older Chinese men and women: A cross-sectional study
Associated factors and health impact of sarcopenia in older Chinese men and women: A cross-sectional study
复制标题
DOI：
10.1159/000107355
复制
发表时间：
2007-01-01
期刊：
影响因子：
3.5
通讯作者：
Woo, Jean
中科院分区：
文献类型：
--
作者：
Lee, Jenny S. W.;Auyeung, Tung-Wai;Woo, Jean
背景：骨质疏松症越来越多地被认为是老年虚弱的一个特征，并与西方人群的不良健康结局有关。人们对亚洲老年人群中的骨质疏松症知之甚少。目的：本研究旨在研究骨质疏松症与常见慢性病、生活方式因素、心理社会幸福感和体能表现之间的关系。方法：对4,000名6~65岁中国社区老年人进行问卷调查。记录疾病、吸烟、饮酒、体力活动水平和心理社会幸福感得分。测量的体能表现包括握力、计时站椅、步长和计时6米步行。采用双能X线骨密度仪测量肌肉质量。采用单变量和多变量分析方法分析附件骨骼肌重(ASM/Ht(2))与多变量之间的关系。结果：平均ASM/Ht(2)男性为7.19 kg/m(2)，女性为6.05 kg/m(2)。年龄较大、吸烟、慢性肺部疾病、动脉粥样硬化、体重不足和缺乏体力活动与调整后的ASM低相关，这反过来又与男性较差的身体健康相关。在调整年龄后，在男女中，较低的阑尾肌质量与较弱的握力有关。在男性中，下肢测试(椅子站立、行走速度和步长)与ASM无关，而在女性中，较低的肌肉质量与较差的下肢肌肉表现无关。结论：居住在社区的中国老年男性和女性的骨量减少与吸烟、慢性病、体重不足、缺乏运动、幸福感较差和上肢体能表现有关。版权所有(C)2007 S.Karger AG，巴塞尔。
Background: Sarcopenia is increasingly being recognized as a feature of frailty in old age and is associated with unfavorable health outcomes in Western populations. Little is known about sarcopenia among Asian elderly populations. Objectives: The study was undertaken to study the association between sarcopenia and common chronic illnesses, lifestyle factors, psychosocial well-being and physical performance. Methods: 4,000 community-dwelling Chinese elderly >= 6 65 years were recruited. Medical illnesses, cigarette smoking, alcohol consumption, physical activity level and psychosocial well-being scores were recorded. Physical performance measured included grip strength, timed chair-stands, stride length and a timed 6-meter walk. Muscle mass was measured using dual-energy X-ray absorptiometry. Relationships between appendicular skeletal muscle mass ( ASM/ ht(2)) and multiple variables were analyzed using uni-and multivariate analyses. Results: Mean ASM/ ht(2) was 7.19 and 6.05 kg/m(2) in men and women respectively. Older age, cigarette smoking, chronic lung disease, atherosclerosis, underweight, and physical inactivity were associated with low adjusted ASM, which was in turn associated with poorer physical wellbeing in men. After adjustment to age, lower appendicular muscle mass was associated with weaker grip strength in both sexes. In men, lower limb tests ( chair-stands, walking speed and step length) were not related to ASM, while in women, lower muscle mass was not associated with poorer lower limb muscle performance. Conclusions: Sarcopenia in community-dwelling older Chinese men and women was associated with cigarette smoking, chronic illnesses, underweight, physical inactivity, poorer well-being and upper limb physical performance. Copyright (C) 2007 S. Karger AG, Basel.