EFFECTS OF SNAKE VENOM ON RABBIT BASOPHIL LEUKOCYTES
EFFECTS OF SNAKE VENOM ON RABBIT BASOPHIL LEUKOCYTES
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DOI：
10.1016/0006-2952(62)90086-2
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发表时间：
1962-01-01
影响因子：
5.8
通讯作者：
OBERER, D
中科院分区：
文献类型：
--
作者：
MARKS, BH;OBERER, D
兔对鳄鱼蛇毒的治疗反应为生物相嗜碱性反应。蛇毒中卵磷脂酶A的含量可以令人满意地解释兔血中嗜碱性粒细胞迅速耗尽的原因，而其他机制，可能是内分泌，可能解释了延迟反应。除卵磷脂酶A外的其他成分对兔的毒杀作用主要是由卵磷脂A引起的。
Rabbits respond to treatment with Crotalus atrox venom with a biophasic basopenic response. The lecithinase A content of snake venom may satisfactorily account for the rapid depletion of basophils in rabbit blood, while other mechanisms, possibly endocrine, may account for the delayed response. Constituents other than lecithinase A are responsible for the major portion of the lethal action of Crotalus atrox venom in rabbits.