Wegener's granulomatosis causing deafness
Wegener's granulomatosis causing deafness
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韦格纳肉芽肿病导致耳聋
DOI：
10.1017/s0022215100077136
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发表时间：
1973
期刊：
影响因子：
--
通讯作者：
F. Bauer
中科院分区：
文献类型：
--
作者：
I. Friedmann;F. Bauer
韦格纳肉芽肿病首先由F. Wegener于1936年和1939年提出的一种新的呼吸道炎性病变，包括三种主要病变：呼吸道的坏死性肉芽肿性病变、全身性局灶性坏死性血管炎和坏死性肾小球炎。上呼吸道通常受到影响，鼻腔或鼻旁腔通常是出现病变的部位。韦格纳最初将该综合征描述为“致炎性”肉芽肿是基于这一特征。其他表现部位包括鼻窦、口腔、喉、皮肤、眼眶（眼眶假瘤）和耳朵。
WEGENER'S granulomatosis, first described in detail by F. Wegener in 1936 and 1939, consists of three principal lesions: necrotizing granulomatous lesions of the respiratory tract, generalized focal necrotizing vasculitis, and necrotizing glomerulitis. The upper respiratory tract is commonly affected and the nasal or paranasal cavities are usually the site of the presenting lesion. Wegener's original descriptive term of the syndrome as 'rhinogenic' granuloma is based on this feature. .Other sites of presentation include the sinuses, oral cavity, the larynx, the skin, the orbit (orbital pseudo-tumour), and the ears.