Incidence and types of childhood esotropia - A population-based study
Incidence and types of childhood esotropia - A population-based study
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DOI：
10.1016/j.ophtha.2006.05.072
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发表时间：
2007-01-01
期刊：
影响因子：
13.7
通讯作者：
Burke, James P.
中科院分区：
文献类型：
--
作者：
Greenberg, Amy E.;Mohney, Brian G.;Burke, James P.
目的：描述儿童内斜视的发病率和类型，在一个明确的population.Design：回顾性人群为基础的coherents.Participants：所有儿童（< 19岁）的居民Olmsted县，明尼苏达州，诊断为内斜视（>= 10棱镜屈光度）从1985年1月1日至1994年12月31日。研究方法：通过罗切斯特流行病学项目的资源确定的所有潜在患者的医疗记录进行了审查。主要结果测量：儿童内斜视的发病率和类型。在这10年期间，共发现了385例儿童内斜视病例，经年龄和性别调整后的年发病率为111.0（95%置信区间，99.9-122.1）/10万例19岁以下患者。这一比率相当于所有6岁以下儿童的累积患病率约为2.0%，年龄较大的儿童患病率显著下降（P < 0.0001）。在385名研究儿童中，诊断的内斜视的具体形式和百分比如下：完全矫正，140获得性非梗阻性黄疸64例内斜视合并中枢神经系统异常44例（11.4%）;部分缓解，39（10.1%）;先天性，31（8.1%）;感觉，25（6.5%）;瘫痪，25（6.5%）;待定，13人（3.4%）;其他，4（1.0%）。结论：儿童内斜视的发病率从这个自我参考的人群-研究结果与西方人群报告的患病率相当。内斜视在生命的前十年最常见，其中最常见的是矫正性和获得性非矫正性形式。先天性、感觉性和麻痹性儿童内斜视在这一人群中较少见。
Objective: To describe the incidence and types of childhood esotropia in a defined population.Design: Retrospective population-based cohort.Participants: All pediatric (< 19 years of age) residents of Olmsted County, Minnesota, diagnosed with an esodeviation (>= 10 prism diopters) from January 1, 1985, through December 31, 1994. Methods: The medical records of all potential patients identified by the resources of the Rochester Epidemiology Project were reviewed.Main Outcome Measures: Incidence and types of childhood esotropia.Results: Three hundred eighty-five cases of childhood esotropia were identified during the 10-year period, yielding an annual age- and gender-adjusted incidence of 111.0 (95% confidence interval, 99.9-122.1) per 100 000 patients younger than 19 years of age. This rate corresponds to a cumulative prevalence of approximately 2.0% of all children younger than 6 years, with a significant decrease in older ages (P < 0.0001). Of the 385 study children, the specific forms and percentages of esotropia diagnosed were as follows: fully accommodative, 140 (36.4%); acquired nonaccommoclative, 64 (16.6%); esotropia associated with an abnormal central nervous system, 44 (11.4%); partially accommodative, 39 (10.1%); congenital, 31 (8.1%); sensory, 25 (6.5%); paralytic, 25 (6.5%); undetermined, 13 (3.4%); and other, 4 (1.0%).Conclusions: The incidence of childhood esotropia from this self-referred population-based study is comparable with prevalence rates reported among Western populations. Esotropia is most common during the first decade of life, with the accommodative and acquired nonaccommoclative forms occurring most frequently. The congenital, sensory, and paralytic forms of childhood esotropia were less common in this population.