Arabinogalactan proteins: focus on carbohydrate active enzymes.

Arabinogalactan proteins: focus on carbohydrate active enzymes.
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DOI:
10.3389/fpls.2014.00198
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发表时间:
2014
影响因子:
5.6
通讯作者:
Geshi N
Geshi N
中科院分区:
生物学2区
文献类型:
--
作者:
Knoch E;Dilokpimol A;Geshi N

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阿拉伯半乳聚糖蛋白(AGPs)是一类高度多样化的细胞表面蛋白聚糖,通常存在于大多数植物物种中。AGP在植物发育过程中的许多细胞过程中发挥重要作用,如生殖、细胞增殖、格局形成和生长以及植物与微生物的相互作用。然而,人们对其功能的分子机制知之甚少。许多使用识别不同AGP聚糖表位的单克隆抗体的研究表明,在植物细胞发育的特定阶段,AGP聚糖的外观略有改变。因此,预期AGP聚糖的生物合成和降解在发育过程中受到严格调控。然而,直到最近,人们对参与AGP聚糖代谢的酶知之甚少。本文综述了近年来发现的参与AGP聚糖生物合成和降解的碳水化合物活性酶(CAZy; http://www.cazy.org/),并讨论了这些酶在植物发育中的生物学作用。
Arabinogalactan proteins (AGPs) are a highly diverse class of cell surface proteoglycans that are commonly found in most plant species. AGPs play important roles in many cellular processes during plant development, such as reproduction, cell proliferation, pattern formation and growth, and in plant-microbe interaction. However, little is known about the molecular mechanisms of their function. Numerous studies using monoclonal antibodies that recognize different AGP glycan epitopes have shown the appearance of a slightly altered AGP glycan in a specific stage of development in plant cells. Therefore, it is anticipated that the biosynthesis and degradation of AGP glycan is tightly regulated during development. Until recently, however, little was known about the enzymes involved in the metabolism of AGP glycans. In this review, we summarize recent discoveries of carbohydrate active enzymes (CAZy; http://www.cazy.org/) involved in the biosynthesis and degradation of AGP glycans, and we discuss the biological role of these enzymes in plant development.
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