The association between alcohol misuse and suicidal behaviour
The association between alcohol misuse and suicidal behaviour
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DOI：
10.1093/alcalc/agl060
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发表时间：
2006-09-01
影响因子：
2.8
通讯作者：
Brady, John
中科院分区：
文献类型：
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作者：
Brady, John
尽管最近整体自杀率略有下降，但25-44岁人群的自杀率仍然很高。本文的目的是研究酒精滥用/消费和自杀行为之间的联系的证据，探讨这种关联的原因，并考虑降低自杀行为的影响。方法：通过Medline检索，查找相关研究证据。结果如下：有证据表明，酒精滥用通过其抑郁症的影响和促进不良生活事件而易导致自杀行为，这两种行为可能具有共同的遗传倾向。急性酒精使用也可以通过诱导负面情绪和损害解决问题的能力，以及加重冲动的人格特征，可能通过对神经递质的影响，促使自杀行为。结论：对问题饮酒的有效干预可能有助于降低自杀率。在公共卫生层面，减少总体酒精消费量可能是有益的，在这方面最有效的措施是旨在限制酒精供应的措施。
Aims: Despite recent small reductions in overall suicide rates, rates among those aged 25-44 have remained high. The aim of this paper was to examine the evidence for a link between alcohol misuse/consumption and suicidal behaviour, explore the reasons for this association, and consider the implications for reducing rates of suicidal behaviour. Methods: A medline search was performed to find relevant research evidence. Results: There is evidence to suggest alcohol misuse predisposes to suicidal behaviour through its depressogenic effects and promotion of adverse life events, and both behaviours may share a common genetic predisposition. Acute alcohol use can also precipitate suicidal behaviours through induction of negative affect and impairment of problem-solving skills, as well as aggravation of impulsive personality traits, possibly through effects on serotonergic neurotransmission. Conclusions: Effective interventions for problem drinking may help reduce suicide rates. At a public health level, reducing overall alcohol consumption may be beneficial, and the measures shown to be most effective in this regard are those that aim to restrict availability of alcohol.