ENDOCRINE EFFECTS OF THE COLD PRESSOR TEST - RELATIONSHIPS TO SUBJECTIVE PAIN APPRAISAL AND COPING
ENDOCRINE EFFECTS OF THE COLD PRESSOR TEST - RELATIONSHIPS TO SUBJECTIVE PAIN APPRAISAL AND COPING
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DOI：
10.1016/0165-1781(84)90028-3
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发表时间：
1984-01-01
影响因子：
11.3
通讯作者：
BUNNEY, WE
中科院分区：
文献类型：
--
作者：
BULLINGER, M;NABER, D;BUNNEY, WE
14 名正常志愿者之前、将非惯用手浸入冰水中 1 分钟后立即抽血（冷加压测试），以及在恢复期间抽血两次。测定β-内啡肽、皮质醇、催乳素、生长激素和阿片类活性的血清水平，并获得主观疼痛评估和应对方式的测量。皮质醇是唯一一个随着有害刺激而显着增加的变量。相关分析得出了神经内分泌变量与主观疼痛评估以及应对方式之间的关系，表明人类疼痛中神经内分泌和心理过程之间存在复杂的相互作用。
Blood was drawn from 14 normal volunteers twice before, immediately after a 1-min immersion of the nondominant hand in ice water (cold pressor test) and twice during recovery. Serum levels of .beta.-endorphin, cortisol, prolactin, growth hormone and opioid activity were determined, and measures of subjective pain appraisal and coping styles were obtained. Cortisol was the only variable to show a significant increase as a function of noxious stimulation. Correlational analysis yielded relationships between neuroendocrine variables and subjective pain appraisal as well as coping styles, suggesting complex interactions between neuroendocrine and psychological processes in human pain.