The in vivo adherence intervention for at risk adolescents with asthma: report of a randomized pilot trial.
The in vivo adherence intervention for at risk adolescents with asthma: report of a randomized pilot trial.
复制标题
对哮喘高危青少年的体内依从性干预：一项随机试点试验的报告。
DOI：
10.1093/jpepsy/jsr107
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发表时间：
2012
影响因子：
3.6
通讯作者：
Darbie,Lynn
中科院分区：
文献类型：
--
作者：
Seid,Michael;D'Amico,ElizabethJ;Varni,JamesW;Munafo,JenniferK;Britto,MariaT;Kercsmar,CarolynM;Drotar,Dennis;King,EileenC;Darbie,Lynn
低收入和少数民族青少年哮喘预后不良的风险很高，部分原因是依从性。我们测试了低社会经济地位（SES）的少数民族青年中度和重度持续性哮喘的依从性干预的可接受性、可行性和效果大小。（n =12;哮喘教育，动机访谈，解决问题技能培训，1个月手机与定制短信）与对照组（n =14;哮喘教育;没有定制消息的手机）。计算效果大小的相对变化从基线（1和3个月）。ResultsIntervention被判断为可接受的和可行的参与者。参与者（12-18岁，平均值= 15.1，SD =1.67）为76.9%的非洲裔美国人，80.7%的公众/无保险。在1个月和3个月时，哮喘症状（Cohen'sd's = 0.40，0.96）和HRQOL（PedsQL™; Cohen'sd's = 0.23，1.25）具有临床意义的中等至大的效应大小。
ObjectiveLow-income and minority adolescents are at high risk for poor asthma outcomes, due in part to adherence. We tested acceptability, feasibility, and effect sizes of an adherence intervention for low socioeconomic status (SES) minority youth with moderate- and severe-persistent asthma.Design and MethodsSingle-site randomized pilot trial: intervention (n =12; asthma education, motivational interviewing, problem-solving skills training, 1 month cell-phone with tailored text messaging) versus control (n =14; asthma education; cell-phone without tailored messaging). Calculated effect-sizes of relative change from baseline (1 and 3 months).ResultsIntervention was judged acceptable and feasible by participants. Participants (12–18 years, mean = 15.1,SD =1.67) were 76.9% African-American, 80.7% public/no insurance. At 1 and 3 months, asthma symptoms (Cohen'sd's= 0.40, 0.96) and HRQOL (PedsQL™; Cohen'sd's = 0.23, 1.25) had clinically meaningful medium to large effect sizes.ConclusionsThis intervention appears promising for at-risk youth with moderate- and severe-persistent asthma.