Interobserver variability of modified Ferriman-Gallwey hirsutism score in a Turkish population
Interobserver variability of modified Ferriman-Gallwey hirsutism score in a Turkish population
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DOI：
10.1007/s00404-008-0747-8
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发表时间：
2009-04-01
影响因子：
2.6
通讯作者：
Cetin, Ahmet
中科院分区：
文献类型：
--
作者：
Api, Murat;Badoglu, Beyhan;Cetin, Ahmet
本研究的目的是评估土耳其人群中每个身体区域的改良Ferriman-Gallwey（mFG）多毛症评分的观察者间差异，采用同时mFG评分设计的横断面研究。观察员不与受试者进行任何访谈，并对先前的评分结果设盲。分析包括一致性百分比，kappa系数，Bland和Altman图，置信区间，最小和最大kappa系数。该研究在一家教学和研究医院进行。对121名土耳其妇女进行了研究，这些妇女没有任何体毛过多的投诉。干预措施包括两名受过特殊训练的医生，两组均采用同步和独立的mFG评分，主要观察指标为各身体部位的mFG评分，一致性分析显示两组医师的评分结果相当一致。9个部位的平均kappa值为0.744，上背部的kappa值最高，上唇的kappa值最低，分别为D-o = 0.847和D-o = 0.585。在9个区域中，两位研究人员的最高（上唇）和最低（手臂）平均范围得分分别为1.46-1.55和0.17-0.12。两名观察者的mFG评分分别只有68.6%和67.8%等于或低于8分。观察到上唇具有身体雄激素敏感区的最高评分以及最高的观察者间变异性。诊断多毛症的临界值应具有人群特异性。
The aim of the study was to evaluate the interobserver variability of modified Ferriman-Gallwey (mFG) hirsutism scores on each body area in a Turkish population.A cross-sectional study of simultaneous mFG scoring design was used. Observers did not make any interview with the subjects and were masked to the previous score results. Analyses included percentage of agreement, kappa coefficients, the Bland and Altman plot, confidence intervals, minimum and maximum kappa coefficients.The study was performed at a teaching and research hospital.Hundred and twenty-one Turkish women without any complaints of excessive body hair were studied.Interventions included two special trained physicians, simultaneous and independent mFG scoring.The main outcome measures were mFG scores in each body area.Agreement analysis demonstrated that the scores of the two physicians were quite concordant. The mean kappa value for nine body area was 0.744 and the highest kappa values from the upper back and the lowest kappa values from the upper lip revealed D-o = 0.847, D-o = 0.585, respectively. The highest (upper lip) and the lowest (arm) mean range scores for the two researchers among the 9 areas were 1.46-1.55 and 0.17-0.12, respectively. Only 68.6 and 67.8% of the mFG scores observed by each of the two observers were equal or below 8.The mFG scoring system was found to be clinically useful. The upper lip was observed to have the highest score of androgen sensitive area of the body as well as the highest interobserver variability. The cut-off value to establish the diagnosis of hirsutism should be population-specific.