Racial Disparities in COVID-19 Hospitalization and In-hospital Mortality at the Height of the New York City Pandemic.

Racial Disparities in COVID-19 Hospitalization and In-hospital Mortality at the Height of the New York City Pandemic.
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DOI:
10.1007/s40615-020-00872-x
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发表时间:
2021-10
影响因子:
3.9
通讯作者:
Jamorabo DS
Jamorabo DS
中科院分区:
医学4区
文献类型:
--
作者:
Renelus BD;Khoury NC;Chandrasekaran K;Bekele E;Briggs WM;Ivanov A;Mohanty SR;Jamorabo DS

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调查种族是否与纽约市(NYC)冠状病毒病患者2019年(新冠肺炎)大流行高峰期的住院和出院存活时间差异有关。对纽约大学附属医院3/10/20至4/13/20住院的新冠肺炎患者进行单中心回顾性队列研究,随访至5/1/20。我们的主要终点是确诊为新冠肺炎的患者与基于种族的地区人口的住院率比较。我们的次要终点存活到出院的住院新冠肺炎患者。纽约市卫生部的数据被用来计算住院优势比。分类变量和连续变量的比较分别采用卡方检验和t检验。使用COX比例风险回归和预测分析进一步研究我们的终点。在我们的分析中,我们的734名患者包括355名女性(48.4%)、372名黑人(50.7%)、214名白人(29.2%)和92名拉美裔(12.5%)。黑人因新冠肺炎而住院的可能性几乎是白人的两倍(OR1.89,95%CI,1.59-2.24,p < 0.001)。与白人相比,拉美裔也更有可能因新冠肺炎而遭受住院死亡率(HR 1.84;95%CI 1.21-2.8;p =0.005)。与白人相比,黑人的住院死亡率风险没有显著增加(HR,1.3;95%CI,0.95-1.78;p =0.09)。黑人比白人更有可能因新冠肺炎而住院,而西班牙裔更有可能经历住院死亡。需要在全国范围内进一步调查新冠肺炎患者存活率和需要住院治疗的严重程度的种族差异背后的社会经济因素。
Investigate whether or not race is associated with differences in hospitalization and survival to discharge among patients with coronavirus disease-2019 (COVID-19) at the height of the pandemic in New York City (NYC). Single-center retrospective cohort study of COVID-19 patients hospitalized at our university-affiliated NYC hospital from 3/10/20 through 4/13/20 with follow-up to 5/1/20. Our primary endpoint was hospitalization rate among patients with confirmed COVID-19 compared with the regional population based on race. Our secondary endpoint survival to discharge among hospitalized COVID-19 patients. NYC Department of Health data were used to calculate hospitalization odds ratios. Chi-square and t tests were used to compare categorial and continuous variables, respectively. Cox proportional hazards regression and predictive analysis were used to investigate our endpoints further. Our cohort of 734 patients included 355 women (48.4%), 372 Blacks (50.7%), 214 Whites (29.2%), and 92 Hispanics (12.5%) in our analysis. Blacks were nearly twice as likely as Whites to require hospitalization for COVID-19 (OR 1.89, 95% CI, 1.59–2.24, p < 0.001). Hispanics were also more likely to suffer in-hospital mortality from COVID-19 compared with Whites (HR 1.84; 95% CI 1.21–2.80; p = 0.005). There was a non-significant increased hazard of in-hospital mortality among Blacks when compared with Whites (HR, 1.30; 95% CI, 0.95–1.78; p = 0.09). Blacks were more likely than Whites to require hospitalization for COVID-19 while Hispanics were more likely to experience in-hospital mortality. Further investigation into the socioeconomic factors underlying racial disparities in COVID-19 survival and severity requiring hospitalization is needed on a national scale.
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