Multiple whole genome alignments and novel biomedical applications at the VISTA portal
Multiple whole genome alignments and novel biomedical applications at the VISTA portal
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DOI：
10.1093/nar/gkm279
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发表时间：
2007-07-01
影响因子：
14.9
通讯作者：
Dubchak, Inna
中科院分区：
文献类型：
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作者：
Brudno, Michael;Poliakov, Alexander;Dubchak, Inna
VISTA比较基因组学门户旨在为生物医学科学家提供一套统一的工具，引导他们从原始DNA序列通过比对和注释到结果的可视化。VISTA门户网站还托管了我们小组计算的许多基因组的比对，允许用户研究他们感兴趣的区域，而无需手动下载单个序列。在这里，我们描述了各种算法和功能的改进，在VISTA门户网站在过去的2年。VISTA门户网站可访问http://genome.lbl.gov/vista。
The VISTA portal for comparative genomics is designed to give biomedical scientists a unified set of tools to lead them from the raw DNA sequences through the alignment and annotation to the visualization of the results. The VISTA portal also hosts the alignments of a number of genomes computed by our group, allowing users to study the regions of their interest without having to manually download the individual sequences. Here we describe various algorithmic and functional improvements implemented in the VISTA portal over the last 2 years. The VISTA Portal is accessible at http://genome.lbl.gov/vista.