Enhancing Genomic Laboratory Reports: A Qualitative Analysis of Provider Review
Enhancing Genomic Laboratory Reports: A Qualitative Analysis of Provider Review
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DOI：
10.1002/ajmg.a.37573
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发表时间：
2016-05-01
影响因子：
2
通讯作者：
Williams, Marc S.
中科院分区：
文献类型：
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作者：
Williams, Janet L.;Rahm, Alanna Kulchak;Williams, Marc S.
本研究报告了医生的反应，他们审查了旨在交流全基因组测序结果的基因组实验室报告的提供者和患者版本。半结构化访谈解决了概念沟通，元素和格式的例子基因组报告。对编码转录本的分析导致围绕基因组测序结果的交流认识到三个结构：（1）提供者同意全基因组测序结果是复杂的，他们欢迎提供支持性解释信息以伴随测序结果的报告;（2）提供者强烈支持包括积极临床指导的报告，例如参考实践指南（如果可用）;和（3）提供者重视基因组报告作为一种资源，将作为促进与患者和家属交流基因组测序结果的基础。提供者重视这两个版本的报告，尽管他们确认需要一份面向提供者的报告。该报告的关键要素包括解释结果的明确语言，以及随着时间的推移为患者的临床护理提供明确指导的综合而全面的预后信息。最重要的是，这种设计的报告不仅有可能返回结果，而且还可以作为一种沟通工具，帮助提供者和患者随着时间的推移讨论和协调护理。(C)2016年6月，作者。美国医学遗传学杂志A部分由Wiley Periodicals，Inc.出版。
This study reports on the responses of physicians who reviewed provider and patient versions of a genomic laboratory report designed to communicate results of whole genome sequencing. Semi-structured interviews addressed concept communication, elements, and format of example genome reports. Analysis of the coded transcripts resulted in recognition of three constructs around communication of genome sequencing results: (1) Providers agreed that whole genomic sequencing results are complex and they welcomed a report that provided supportive interpretation information to accompany sequencing results; (2) Providers strongly endorsed a report that included active clinical guidance, such as reference to practice guidelines, if available; and (3) Providers valued the genomic report as a resource that would serve as the basis to facilitate communication of genome sequencing results with their patients and families. Providers valued both versions of the report, though they affirmed the need for a provider-oriented report. Critical elements of the report included clear language to explain the result, as well as consolidated yet comprehensive prognostic information with clear guidance over time for the clinical care of the patient. Most importantly, it appears a report with this design has the potential not only to return results but also serves as a communication tool to help providers and patients discuss and coordinate care over time. (C) 2016 The Authors. American Journal of Medical Genetics Part A published by Wiley Periodicals, Inc.