Thyroid and the heart.

Thyroid and the heart.
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DOI:
10.1016/j.amjmed.2014.03.009
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发表时间:
2014-08
影响因子:
5.9
通讯作者:
Sowers, James R.
Sowers, James R.
中科院分区:
医学2区
文献类型:
--
作者:
Grais, Ira Martin;Sowers, James R.

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甲状腺激素调节心血管系统的每一个组成部分,是正常心血管发育和功能所必需的。当存在心血管疾病时,甲状腺功能检查是特征性的指示,以确定是否存在明显的甲状腺疾病或甚至亚临床功能障碍。由于甲状腺功能减退、高血压和心血管疾病都随着年龄的增长而增加,监测TSH(甲状腺功能减退最敏感的检测方法)在这一不断扩大的人群中非常重要。更好地了解甲状腺激素状态对心血管生理的影响,将使卫生保健提供者能够在评估和治疗高血压和心血管疾病的同时,就甲状腺激素的评估和治疗做出决定。本综述的目的是了解甲状腺激素对正常心血管功能的影响,以及甲状腺功能减退和甲亢在多种心血管疾病中的潜在作用。
Thyroid hormones modulate every component of the cardiovascular system necessary for normal cardiovascular development and function. When cardiovascular disease is present, thyroid function tests are characteristically indicated to determine if overt thyroid disorders or even subclinical dysfunction exists. As hypothyroidism, hypertension and cardiovascular disease all increase with advancing age monitoring of TSH, the most sensitive test for hypothyroidism, is important in this expanding segment of our population. A better understanding of the impact of thyroid hormonal status on cardiovascular physiology will enable health care providers to make decisions regarding thyroid hormone evaluation and therapy in concert with evaluating and treating hypertension and cardiovascular disease. The goal of this review is to access contemporary understanding of the effects of thyroid hormones on normal cardiovascular function and the potential role of overt and subclinical hypothyroidism and hyperthyroidism in a variety of cardiovascular diseases.
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