Development and Testing of a Vaginal Pressure Sensor to Measure Intra-abdominal Pressure in Women
Development and Testing of a Vaginal Pressure Sensor to Measure Intra-abdominal Pressure in Women
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DOI：
10.1002/nau.20794
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发表时间：
2010-01-01
影响因子：
2
通讯作者：
Nygaard, Ingrid E.
中科院分区：
文献类型：
--
作者：
Rosenbluth, Evan M.;Johnson, Paul J.;Nygaard, Ingrid E.
目的：腹内压升高(IAP)可能是盆底疾病的一个潜在的可改变的危险因素。然而，由于缺乏适合在现实世界环境中测量腹压的仪器，存在的证据有限。这项研究的目的是开发和测试一种用于测量女性腹内压的阴道传感器原型。方法：采用1.2×3 cm径向对称硅胶胶囊封装压力敏感电路板，研制了一种非定向阴道传感器。我们在一个标准化的压力室中对反应进行了表征。8名女性在接受充盈膀胱测定法时，在阴道内佩戴了传感器。我们将咳嗽、Valsalva、蹲下和跳跃时的峰值压力与使用10号法国直肠气囊尿流动力学导管获得的峰值压力进行了比较。我们计算了每个事件的直肠和阴道感受器之间的皮尔逊相关系数。结果：在最初的台架试验中，阴道传感器表现出线性响应。各探头与直肠球囊导管相关性良好(r分别为0.97、0.94、0.97)。然而，直肠气囊导管在跳跃过程中记录到更高的峰值和更低的低谷压力，通常是负压。阴道感应器没有显示这样的伪影。结论：该阴道压力传感器可作为测量非晚期脱垂妇女腹内压的替代方法。通过测量生理来源的压力，阴道传感器比电流传感器更不容易受到外部噪音和误差的影响。使用这个原型，我们接下来将开发一个远程无线版本，以捕获在实验室环境之外体验到的一系列腹部压力。诺鲁罗。乌罗代南。29：532-，2010。(C)2010年Wiley-Liss公司
Aims: Elevated intra-abdominal pressure (IAP) may be a potentially modifiable risk factor for pelvic floor disorders. However, limited evidence exists due to the lack of instruments suitable to measure abdominal pressures in real world settings. The aim of this study was to develop and test a vaginal sensor prototype to measure intra-abdominal pressure in women. Methods: We developed a non-directional vaginal sensor by housing pressure-sensing circuit boards in 1.2 x 3 cm radially symmetric silicon capsules. We characterized the response in a standardized pressure chamber. Eight women wore a sensor intra-vaginally while undergoing filling cystometry. We compared peak pressures during coughing, valsalva, squatting, and jumping to those obtained using a #10 French rectal balloon urodynamics catheter. We calculated Pearson's correlation coefficients between rectal and vaginal sensors for each event. Results: The vaginal sensors exhibited linear responses during initial bench testing. Each transducer correlated well with the rectal balloon catheter during coughing, valsalva, and squatting (r = 0.97, 0.94, and 0.97, respectively). However, the rectal balloon catheter recorded higher peak and lower, often negative, trough pressures during jumping. The vaginal sensor showed no such artifact. Conclusions: This vaginal pressure sensor can be used as a surrogate for measuring intra-abdominal pressure in women without advanced prolapse. By measuring pressure at the physiological source, the vaginal sensor is less prone to extraneous noise and error than current transducers. Using this prototype, we will next develop a remote wireless version to capture a range of abdominal pressures experienced outside of the laboratory setting. Neurourol. Urodynam. 29:532-535, 2010. (C) 2010 Wiley-Liss, Inc.