GenBank.

GenBank.
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DOI:
10.1093/nar/gkn723
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发表时间:
2009-01
影响因子:
14.9
通讯作者:
Sayers EW
Sayers EW
中科院分区:
生物学2区
文献类型:
--
作者:
Benson DA;Karsch-Mizrachi I;Lipman DJ;Ostell J;Sayers EW

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GenBank®是一个综合性数据库,包含30多万种以属级或更低级别命名的生物体的公开核苷酸序列,主要通过单个实验室提交和大规模测序项目的批量提交获得。大多数提交是使用基于网络的BankIt或独立的Sequin程序进行的,并且登录号由GenBank®工作人员在收到后分配。与欧洲的欧洲分子生物学实验室核苷酸序列数据库和日本DNA数据库每日交换数据,确保覆盖全球。GenBank可通过美国国家生物技术信息中心(NCBI)检索系统访问,该系统将来自主要DNA和蛋白质序列数据库的数据与分类学、基因组、作图、蛋白质结构和结构域信息以及通过PubMed的生物医学期刊文献沿着。BLAST提供GenBank和其他序列数据库的序列相似性检索。基因库数据库的完整双月发布和每日更新可通过FTP获得。要访问GenBank及其相关检索和分析服务,请开始访问NCBI主页:www.ncbi.nlm.nih.gov。
GenBank® is a comprehensive database that contains publicly available nucleotide sequences for more than 300 000 organisms named at the genus level or lower, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and accession numbers are assigned by GenBank® staff upon receipt. Daily data exchange with the European Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the National Center for Biotechnology Information (NCBI) Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage: www.ncbi.nlm.nih.gov.