Severe Acute Respiratory Syndrome Coronavirus 2 RNA in Plasma Is Associated With Intensive Care Unit Admission and Mortality in Patients Hospitalized With Coronavirus Disease 2019
Severe Acute Respiratory Syndrome Coronavirus 2 RNA in Plasma Is Associated With Intensive Care Unit Admission and Mortality in Patients Hospitalized With Coronavirus Disease 2019
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DOI：
10.1093/cid/ciaa1338
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发表时间：
2021-08-01
影响因子：
11.8
通讯作者：
Berdal, Jan-Erik
中科院分区：
文献类型：
--
作者：
Prebensen, Christian;Myhre, Peder L.;Berdal, Jan-Erik
严重急性呼吸综合征冠状病毒2 RNA在循环中的临床意义尚不清楚。在这项前瞻性队列研究中，我们在2019年因冠状病毒病住院的123名患者中的58名（47%）的血浆中检测到病毒RNA。在入住重症监护室和/或死亡的患者中，RNA检测频率更高，水平更高。
The clinical significance of severe acute respiratory syndrome coronavirus 2 RNA in the circulation is unknown. In this prospective cohort study, we detected viral RNA in the plasma of 58 of 123 (47%) patients hospitalized with coronavirus disease 2019. RNA was detected more frequently, and levels were higher, in patients who were admitted to the intensive care unit and/or died.