[Hodotopical researchonneural pathway of Chinese language in posterior inferior frontal gyrus].
[Hodotopical researchonneural pathway of Chinese language in posterior inferior frontal gyrus].
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DOI：
10.3760/cma.j.issn.0376-2491.2016.17.013
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发表时间：
2016-05-10
影响因子：
--
通讯作者：
Yang, Xuejun
中科院分区：
文献类型：
--
作者：
Lin, Yu;Zhang, Kai;Yang, Xuejun
目的：探讨中国人额下回后神经通路的视端组织结构。方法：对20名志愿者进行重复导航经颅磁刺激（repetitive navigated transcranial magnetic stimulation，nTMS）语言标测，确定额下回后部的语言关键部位，然后利用DTI纤维束成像技术重建额下回后部的语言相关纤维束。结果：（1）18名被试在额下回后部存在诱发重复性语言错误的语言位点;腹侧中央前回、旁环肌和旁角肌的基本语言位点总数分别占39.46%、41%和13%。（2）弓状束长段投射入腹侧中央前回的概率为100%。弓状束前段投射入腹侧中央前回的概率为100%。额枕下束投射入三角肌的概率为94%。钩束投射入三角肌的概率为67%。Aslantfiber有100%的概率投射到旁围肌。（3）当语言中枢位于腹侧中央前回时，与弓状束长段相关的概率为82%。当语言中枢位于旁盖肌时，与斜肌纤维相关的概率为79%。当语言中枢位于三角旁肌时，与额枕下束相关的概率为60%。不同部位的关键语言部位通过不同的神经束传导，这给神经外科医生带来了启示，为了达到最大限度的病灶切除和语言功能保护，我们应该根据每个人的语言局部组织，保护必要的语言皮层和与语言相关的皮层下联系。
OBJECTIVE: To investigate the hodotopical organization of neural pathway of Chinese in posterior inferior frontal gyrus. Forprovide the basis for the individual protectionoflanguage functionin the operation of the language functional area.METHODS: Twenty volunteers underwentlanguage mapping using repetitive navigated transcranial magnetic stimulation(nTMS)to identify the essential language sites in posterior inferior frontal gyrus.Then, DTI tractography was used to reconstruct language-relevant fiber tracts within posterior inferior frontal lobe. Finally, the relationships between essential language sites and language-relevant fiber tracts were analyzed.RESULTS: (1)Eighteen subjects hadlanguage sites which induce repeatable language errors in posterior inferior frontal gyrus. The total number of essential language sites was 39.46% of essential language sites located in ventral precentralgyrus, 41% in parsopercularis and 13% in parstriangularis. (2)Long segment of arcuate fasciculus had the probability of 100%to project into ventral precentralgyrus. Anterior segment of arcuate fasciculus had the probability of 100%to project into ventral precentralgyrus. Inferior frontal occipital fasciculus had the probability of 94% to project into parstriangularis. Uncinate fasciculus had the probability of 67% to project into parstriangularis. Aslantfiber had the probability of 100% to project into parsopercularis.(3)When the essential language site located in ventral precentralgyrus, it had the probability of 82% to correlate with long segment of arcuate fasciculus. When the essential language site located in parsopercularis, it had the probability of 79%to correlate with aslant fiber. When the essential language site located in parstriangularis, it had the probability of 60% to correlate with inferior frontal occipital fasciculus.CONCLUSION: Essential language sites within distinct locations were conducted through different fasciculus, which enlightensour neurosurgeons thatin order to achieve both maximal lesions resection and language function protection, we shouldprotectboththe essential language cortices and language relevant subcortical connection according to each individual's hodotopical organization.