Nutrient profiling and adherence to components of the UK national dietary guidelines association with metabolic risk factors for CVD and diabetes: Airwave Health Monitoring Study.
Nutrient profiling and adherence to components of the UK national dietary guidelines association with metabolic risk factors for CVD and diabetes: Airwave Health Monitoring Study.
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DOI：
10.1017/s0007114518000016
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发表时间：
2018-02
期刊：
影响因子：
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通讯作者：
Rebeca Eriksen;R. Gibson;K. Lamb;Y. Mcmeel;A. Vergnaud;Jeanette Spear;M. Aresu;Q. Chan;P. Elliott;G. Frost
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文献类型：
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作者：
Rebeca Eriksen;R. Gibson;K. Lamb;Y. Mcmeel;A. Vergnaud;Jeanette Spear;M. Aresu;Q. Chan;P. Elliott;G. Frost
CVD是全球死亡的主要原因。饮食是心血管疾病发展的一个关键可改变的组成部分。英国没有官方的饮食质量指数可用于英国营养流行病学研究。本研究的目的是：（i）根据英国饮食参考值（DRV）的组成部分制定饮食质量指数，（ii）确定该指数，现有的英国营养概况（NP）模型和英国成年人群中全面的心脏代谢风险标志物之间的关联。使用来自Airwave健康监测研究（n 5848）的数据进行了横断面分析。通过7天食物日记和代谢风险测量腰围，BMI，血脂谱，糖化血红蛋白（HbA 1c）和血压测量来测量膳食摄入量。采用新的DRV指数和NP模型评估日粮质量。通过多元线性模型和逻辑回归分析饮食和心脏代谢风险之间的关系。NP评分增加2分与总胆固醇（β -0统计学33 mmol/l，P<0.0001）和HbA 1c（β -0统计学01%，P<0.0001）相关。DRV评分增加两个百分点与腰围（β -0 56 cm，P<0·0001）、BMI（β -0 15 kg/m2，P<0·0001）、总胆固醇（β -0 06 mmol/l，P<0·0001）和HbA 1c（β -0 02%，P=0·002）相关。DRV评分增加1分与2型糖尿病（T2 D）（OR 0.94，P= 0.01）和肥胖（OR 0.95，P<0.0001）相关。DRV指数与总体饮食质量和CVD和T2 D的风险因素相关，支持其在调查英国人群CVD风险的营养流行病学研究中的应用。
CVD is the leading cause of death worldwide. Diet is a key modifiable component in the development of CVD. No official UK diet quality index exists for use in UK nutritional epidemiological studies. The aims of this study are to: (i) develop a diet quality index based on components of UK dietary reference values (DRV) and (ii) determine the association between the index, the existing UK nutrient profile (NP) model and a comprehensive range of cardiometabolic risk markers among a British adult population. A cross-sectional analysis was conducted using data from the Airwave Health Monitoring Study (n 5848). Dietary intake was measured by 7-d food diary and metabolic risk using waist circumference, BMI, blood lipid profile, glycated Hb (HbA1c) and blood pressure measurements. Diet quality was assessed using the novel DRV index and NP model. Associations between diet and cardiometabolic risk were analysed via multivariate linear models and logistic regression. A two-point increase in NP score was associated with total cholesterol (β -0·33 mmol/l, P<0·0001) and HbA1c (β -0·01 %, P<0·0001). A two-point increase in DRV score was associated with waist circumference (β -0·56 cm, P<0·0001), BMI (β -0·15 kg/m2, P<0·0001), total cholesterol (β -0·06 mmol/l, P<0·0001) and HbA1c (β -0·02 %, P=0·002). A one-point increase in DRV score was associated with type 2 diabetes (T2D) (OR 0·94, P=0·01) and obesity (OR 0·95, P<0·0001). The DRV index is associated with overall diet quality and risk factors for CVD and T2D, supporting its application in nutritional epidemiological studies investigating CVD risk in a UK population.