Magnetic Resonance Imaging for Diagnosis of Congenital Anosmia
Magnetic Resonance Imaging for Diagnosis of Congenital Anosmia
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磁共振成像诊断先天性嗅觉缺失症
DOI：
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
H. Yamane
中科院分区：
文献类型：
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作者：
T. Aiba;Y. Inoue;Kohji Matsumoto;M. Shakudo;K. Hashimoto;H. Yamane
对9例出生后嗅觉缺乏的患者进行了磁共振成像(MRI)检查。其中7例患者，包括2例Kallmann综合征患者，表现为嗅球、嗅束、嗅沟或直肌回异常，不同患者的异常类型和程度有所不同。另外两名患者嗅觉通路形态正常，不能排除获得性感觉神经性嗅觉障碍的可能性。MRI有助于判断先天性嗅觉缺乏症患者是否存在嗅觉通路异常。许多先天性嗅觉缺失症和嗅觉通路成形术不足或成形术的患者，仍然没有性腺或内分泌疾病。关键词：异常，性腺功能障碍，卡尔曼综合征，嗅球，嗅束，嗅沟，直肌。
Magnetic Resonance Imaging (MRI) was performed on 9 patients who lacked a sense of smell since birth. Seven of them, including two patients with Kallmann syndrome, exhibited abnormality of the olfactory bulb, olfactory tract, olfactory sulcus, or rectus gyrus, with some variation among patients in type and degree of abnormality. The other two patients exhibited normal olfactory pathway morphology, and for them the possibility of acquired sensorineural anosmia could not be ruled out. MRI is useful for determining whether patients with congenital anosmia have olfactory pathway anomalies. Many patients with congenital anosmia and hypoplasty or aplasty of the olfactory pathway nevertheless had no gonadal or endocrinological disorders. Key words: anomaly, gonadal disorder, Kallmann syndrome, olfactory bulb, olfactory tract, olfactory sulcus, rectus gyrus.