Generation of α,β-Unsaturated Platinum Carbenes from Homopropargylic Alcohols: Rearrangements to Polysubstituted Furans
Generation of α,β-Unsaturated Platinum Carbenes from Homopropargylic Alcohols: Rearrangements to Polysubstituted Furans
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DOI：
10.1021/ol202649j
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发表时间：
2011-11-04
期刊：
影响因子：
5.2
通讯作者：
Ferreira, Eric M.
中科院分区：
文献类型：
--
作者：
Allegretti, Paul A.;Ferreira, Eric M.
许多不同取代的呋喃是通过环异构化过程合成的，该过程经过独特的金属卡宾物种。评估配体结构和离去基团的性质。卡宾中间体的特性可以调节，从而产生高选择性的氢或硅基团迁移。
A number of diversely substituted furans are synthesized via a cycloisomerization process that goes through a unique metal carbene species. Both ligand structure and the nature of the leaving group are evaluated. The characteristics of the carbene intermediate can be modulated, resulting in highly selective hydrogen or silicon group migrations.