X-Ray Luminescence and X-Ray Fluorescence Computed Tomography: New Molecular Imaging Modalities
X-Ray Luminescence and X-Ray Fluorescence Computed Tomography: New Molecular Imaging Modalities
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DOI：
10.1109/access.2014.2353041
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发表时间：
2014-01-01
期刊：
影响因子：
3.9
通讯作者：
Xing, Lei
中科院分区：
文献类型：
--
作者：
Ahmad, Moiz;Pratx, Guillem;Xing, Lei
X射线发光和X射线荧光计算机断层扫描（CT）是X射线成像中的两种新兴技术，其提供功能和分子成像能力。两种发射型断层摄影成像模式都使用外部X射线来刺激二次发射，光或二次X射线，然后采集这些二次发射用于断层摄影重建。这些模式超越了当前X射线成像的灵敏度极限，并且具有使X射线成像能够提取分子成像信息的潜力。这些新的模式也有望突破其他体内分子成像模式的空间分辨率限制。本文综述了X射线荧光CT和X射线发光CT的发展及其各自的优点。讨论包括当前的问题和未来的研究方向和这些模式在未来的分子成像应用中的作用。
X-ray luminescence and X-ray fluorescence computed tomography (CT) are two emerging technologies in X-ray imaging that provide functional and molecular imaging capability. Both emission type tomographic imaging modalities use external X-rays to stimulate secondary emissions, either light or secondary X-rays, which are then acquired for tomographic reconstruction. These modalities surpass the limits of sensitivity in current X-ray imaging and have the potential of enabling X-ray imaging to extract molecular imaging information. These new modalities also promise to break through the spatial resolution limits of other in vivo molecular imaging modalities. This paper reviews the development of X-ray luminescence and X-ray fluorescence CT and their relative merits. The discussion includes current problems and future research directions and the role of these modalities in future molecular imaging applications.