Comparison and evaluation of the efficacy of compressed SENSE (CS) and gradient- and spin-echo (GRASE) in breath-hold (BH) magnetic resonance cholangiopancreatography (MRCP)
Comparison and evaluation of the efficacy of compressed SENSE (CS) and gradient- and spin-echo (GRASE) in breath-hold (BH) magnetic resonance cholangiopancreatography (MRCP)
复制标题
压缩 SENSE (CS) 与梯度自旋回波 (GRASE) 在屏气 (BH) 磁共振胰胆管造影 (MRCP) 中的疗效比较和评估
DOI：
10.1002/jmri.26863
复制
发表时间：
2019-07-16
影响因子：
4.4
通讯作者：
Jin, Zhengyu
中科院分区：
文献类型：
--
作者：
He, Ming;Xu, Jin;Jin, Zhengyu
合同资助赞助商中国医学科学院（CAMS）创新医学计划；合同授予号：2017-I2M-1-001；合同资助单位：北京协和医院杰出青年基金；合同授予号：JQ201704；合同资助单位：国家自然科学基金委；合同授予号：81871512；合同资助单位：中国医学科学院国家公益性基础科学研究计划项目；合同授予号：2018PT32003和2017PT32004。背景压缩感知 (CS) 和梯度自旋回波 (GRASE) 序列都可以通过单次屏气 (BH) 实现 3D 磁共振胰胆管造影 (MRCP)。这项工作假设，与传统的导航触发（NT）-MRCP 相比，两种 BH-MRCP 协议 GRASE 和 CS 可以提供更好的成像质量，特别是对于呼吸不规则的患者。目的 评估和比较三种 MRCP 协议的图像质量和诊断性能。研究类型前瞻性。受试者纳入了 74 名疑似患有导管相关病变的患者。场强 3.0T。序列 NT-MRCP、BH-CS-MRCP 和 BH-GRASE-MRCP。评估 根据呼吸波主观评估呼吸规律。比较了采集时间。胰胆系统分为12个部分并按5分制进行评估。对三种 MRCP 的诊断性能进行了评估和比较。统计检验使用带有事后检验的弗里德曼检验、受试者工作特征(ROC)曲线分析、麦克尼马尔检验和肯德尔W检验。结果 BH-MRCP 显着缩短了扫描时间（P < 0.05）。对于呼吸不规则患者，GRASE-MRCP和CS-MRCP的整体影像学评分显着高于NT-MRCP（4.283和4.283 vs. 3.000，均P < 0.05）。与NT-MRCP相比，BH-CS和BH-GRASE MRCP对呼吸不规则患者的诊断性能显着提高（AUC = 0.860和0.863 vs. 0.572，均P < 0.001）。数据结论与传统NT-MRCP相比，BH-CS和BH-GRASE MRCP对于呼吸规则患者的整体成像质量和诊断性能没有显着差异，而对于呼吸不规则患者则显着优于传统NT-MRCP。技术功效：第 2 阶段 J. Magn。共振。影像 2019。
Contract grant sponsor Chinese Academy of Medical Sciences (CAMS) Initiative for Innovative Medicine; Contract grant number: 2017-I2M-1-001; Contract grant sponsor: Outstanding Youth Fund of Peking Union Medical College Hospital; Contract grant number: JQ201704; Contract grant sponsor: National Natural Science Foundation of China; Contract grant number: 81871512; Contract grant sponsor: National Public Welfare Basic Scientific Research Program of Chinese Academy of Medical Sciences; Contract grant numbers: 2018PT32003 and 2017PT32004. Background Both compressed-sensing (CS) and gradient- and spin-echo (GRASE) sequences can achieve 3D magnetic resonance cholangiopancreatography (MRCP) with a single breath-hold (BH). This work hypothesized that compared with conventional navigator-triggered (NT)-MRCP, the two BH-MRCP protocols, GRASE and CS, may provide better imaging quality, especially for patients with irregular breathing. Purpose To evaluate and compare the image quality and diagnostic performance of three MRCP protocols. Study Type Prospective. Subjects Seventy-four patients suspected to have duct-related pathologies were enrolled. Field Strength 3.0T. Sequences NT-MRCP, BH-CS-MRCP, and BH-GRASE-MRCP. Assessment Breath regularity was evaluated subjectively according to the respiratory waves. The acquisition time was compared. The pancreaticobiliary system was divided into 12 segments and evaluated on a 5-point scale. The diagnostic performance of the three MRCPs was evaluated and compared. Statistical Tests The Friedman test with a post-hoc test, receiver operating characteristic (ROC) curve analysis, McNemar test, and Kendall's W test were used. Results The BH-MRCP decreased the scan time significantly (P < 0.05). The overall imaging scores of GRASE-MRCP and CS-MRCP were significantly higher than that of NT-MRCP for patients with irregular breathing (4.283 and 4.283 vs. 3.000, both P < 0.05). Compared with NT-MRCP, the diagnostic performance of BH-CS and BH-GRASE MRCP was significantly improved for patients with irregular breathing (AUC = 0.860 and 0.863 vs. 0.572, both P < 0.001). Data Conclusion Compared with conventional NT-MRCP, the overall imaging quality and diagnostic performance of BH-CS and BH-GRASE MRCP were not significantly different for patients with regular breathing and significantly superior for patients with irregular breathing. Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019.