β(1-3)Glucanosyltransferase Gel4p Is Essential for Aspergillus fumigatus
β(1-3)Glucanosyltransferase Gel4p Is Essential for Aspergillus fumigatus
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DOI：
10.1128/ec.00107-10
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发表时间：
2010-08-01
期刊：
影响因子：
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通讯作者：
Mouyna, Isabelle
中科院分区：
文献类型：
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作者：
Gastebois, Amandine;Fontaine, Thierry;Mouyna, Isabelle
烟曲霉的β（1-3）葡聚糖基转移酶GEL家族包含7个基因，其中只有3个基因在菌丝生长过程中表达。本研究探讨了GEL 4基因的作用。像其他Gelps一样，它编码糖基磷脂酰肌醇（GPI）锚定蛋白。与迄今为止分析的其他β（1-3）葡糖基转移酶相比，它对该真菌物种是必需的。
The beta(1-3) glucanosyltransferase GEL family of Aspergillus fumigatus contains 7 genes, among which only 3 are expressed during mycelial growth. The role of the GEL4 gene was investigated in this study. Like the other Gelps, it encodes a glycosylphosphatidylinositol (GPI)-anchored protein. In contrast to the other beta(1-3)glucanosyltransferases analyzed to date, it is essential for this fungal species.