Health-related quality of life in euthymic bipolar disorder patients: Differences between bipolar I and II subtypes
Health-related quality of life in euthymic bipolar disorder patients: Differences between bipolar I and II subtypes
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DOI：
10.4088/jcp.v68n0205
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发表时间：
2007-02-01
影响因子：
5.3
通讯作者：
Maj, Mario
中科院分区：
文献类型：
--
作者：
Maina, Giuseppe;Albert, Umberto;Maj, Mario
目的：本研究的目的是比较双相I型和II型精神障碍患者的健康相关生活质量(HRQOL)指标。我们选择了一组复发性重度抑郁症(RMD)患者和一组非精神疾病患者作为对照样本。方法：对意大利5个中心招募的253名受试者，包括90例双相I型障碍、52例双相II型障碍、61例RMD和50例健康对照，采用《医学结局研究36项健康调查问卷》(SF-36)进行HRQOL测评。所有受试者都接受了DSM-IV的结构化临床访谈；精神疾病患者在纳入研究之前必须处于至少2个月的愉悦状态，这一点得到了汉密尔顿抑郁总分评定量表的确认
Objective: The aim of the present study was to compare health-related quality of life (HRQoL) measures in euthymic patients with bipolar I and II disorder. We included as comparison samples a group of subjects with recurrent major depression (RMD) and a group of non-psychiatrically ill individuals.Method: HRQoL was assessed using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) in 253 subjects recruited in 5 Italian centers: 90 patients with bipolar I disorder, 52 patients with bipolar II disorder, 61 subjects with RMD and 50 healthy comparison individuals. All subjects were evaluated with the Structured Clinical Interview for DSM-IV; psychiatric patients had to be in a euthymic state for at least 2 months prior to the inclusion in the study, as confirmed by a Hamilton Rating Scale for Depression total score