Epidemiology and clinical presentation of hepatocellular carcinoma
Epidemiology and clinical presentation of hepatocellular carcinoma
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DOI：
10.1016/s1051-0443(07)61783-7
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发表时间：
2002-09-01
影响因子：
2.9
通讯作者：
Di Bisceglie, AM
中科院分区：
文献类型：
--
作者：
Di Bisceglie, AM
肝细胞癌（HCC）是世界范围内最常见的内部恶性肿瘤之一。直到最近，这种情况在西方还很少发生。然而，现在，它在美国和其他西方发达国家的发病率似乎正在上升。最常见的导致HCC的潜在因素是慢性病毒性肝炎和肝硬化。常见的临床特征包括腹痛和肝脏合成功能恶化。然而，最近，由于更频繁的筛查和成像技术的改进，无症状肿瘤患者正在被诊断出来。早期发现HCC是改善治疗结果的关键因素。越来越多的证据表明，肝细胞癌可以通过旨在预防或治疗病毒性肝炎的策略来预防。
Hepatocellular carcinoma (HCC) is one of the most common internal malignancies worldwide. Until recently, it has occurred relatively rarely in the West. Now, however, it appears to be rising in incidence in the United States and other developed western countries. The most frequent underlying factors causing HCC are chronic viral hepatitis and cirrhosis. Common clinical features include abdominal pain and worsening of hepatic synthetic function. More recently, however, patients with asymptomatic tumors are being diagnosed because of more frequent screening and improvements in imaging techniques. Early detection of HCC is a key factor in improving outcomes of therapies. There is growing evidence that HCC may be prevented with strategies aimed at preventing or treating viral hepatitis.