Right Ventricular Doppler Echocardiographic Study of Indeterminate Form of Chagas Disease
Right Ventricular Doppler Echocardiographic Study of Indeterminate Form of Chagas Disease
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DOI：
10.5935/abc.20140197
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发表时间：
2015-03-01
影响因子：
2.6
通讯作者：
Rassi, Salvador
中科院分区：
文献类型：
--
作者：
Furtado, Rogério Gomes;Frota, Daniela do Carmo Rassi;Rassi, Salvador
背景：不确定形式的恰加斯病/心脏正常（ICD/CN）患者表现出正常的心电图和胸部 X 光检查；然而，更复杂的测试检测到心脏存在一定程度的形态和功能变化。 目的：评估 ICD/CN 患者右心室 (RV) 收缩和舒张功能障碍的患病率。方法：这是一项病例对照和患病率研究。使用多普勒二维超声心动图 (2D) 对 92 例患者进行评估并分为两组：I 组（正常，n = 31）和 II 组（ICD/CN，n = 61）。 结果：I 组和 II 组患者的 RV 收缩功能障碍患病率如下：面积变化分数（0.0% 与 0.6%）、三尖瓣环活动度（0.0% 与0.0%）和 S 波组织多普勒（6.4% 与 26.0%，p = 0.016）。总体疾病的患病率，例如使用组织多普勒（16.1% 与 27.8%，p = 0.099）和脉冲多普勒（61.3% 与 68%，p = 0.141）的右心肌性能指数，以及舒张期疾病，例如异常松弛（0.0% 与 6.0%）、假正常模式（0.0% 与 0.0%）和限制性模式（0.0% 与 0.0%） 0.0%）组间无统计学差异。结论：右心室收缩功能障碍的患病率估计为 26%（S 波速度与其他变量相比），表明 ICD/CN 组右心室收缩功能的早期变化。
Background: Patients with indeterminate form of Chagas disease/cardiac normality (ICD/CN) exhibited normal electrocardiograms and chest X-rays; however, more sophisticated tests detected some degree of morphological and functional changes in the heart.Objective: To assess the prevalence of systolic and diastolic dysfunction of the right ventricle (RV) in patients with ICD/CN.Methods: This was a case-control and prevalence study. Using Doppler two-dimensional echocardiography (2D), 92 patients were assessed and divided into two groups: group I (normal, n = 31) and group II (ICD/CN, n = 61).Results: The prevalence of RV systolic dysfunction in patients in groups I and II was as follows: fractional area change (0.0% versus 0.6%), mobility of the tricuspid annulus (0.0% versus 0.0%), and S-wave tissue Doppler (6.4% versus 26.0%, p = 0.016). The prevalence of global disorders such as the right myocardial performance index using tissue Doppler (16.1% versus 27.8%, p = 0.099) and pulsed Doppler (61.3% versus 68%, p = 0.141) and diastolic disorders such as abnormal relaxation (0.0% versus 6.0%), pseudonormal pattern (0.0% versus 0.0%), and restrictive pattern (0.0% versus 0.0%) was not statistically different between groups.Conclusion: The prevalence of RV systolic dysfunction was estimated to be 26% (S wave velocity compared with other variables), suggesting incipient changes in RV systolic function in the ICD/CN group.