Patterns of alcohol use, problem drinking, and HIV infection among high-risk African women
Patterns of alcohol use, problem drinking, and HIV infection among high-risk African women
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DOI：
10.1097/olq.0b013e3181677547
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发表时间：
2008-06-01
影响因子：
3.1
通讯作者：
Kapiga, Saidi H.
中科院分区：
文献类型：
--
作者：
Fisher, Joseph C.;Cook, Peter A.;Kapiga, Saidi H.
目的：研究饮酒模式与HIV感染之间的关系，并在非洲高危女性样本中评估问题饮酒与HIV风险因素流行之间的关系。方法：在一项旨在评估HIV风险因素的前瞻性队列研究中，收集了2002-2003年间1050名女性的基线数据。通过访谈获得有关人口统计和就业特征、性行为和饮酒模式的信息。使用CAGE问卷对问题饮酒进行评估。使用优势比、调整优势比(AOR)和95%可信区间(CI)总结了饮酒与HIV/STD和性行为之间的关系。结果：HIV感染率为19.0%(95%CI，16.6%-21.4%)。总体而言，73.9%的女性饮酒，而34.6%的女性被归类为酗酒者。在调整了人口和就业变量后，与不饮酒者相比，饮酒者感染HIV+的风险更高(AOR，2.10；95%CI，1.29-3.42)。最近的饮酒次数和饮酒量表明，饮酒越多，风险就越高。问题饮酒者感染HIV+的风险高于非问题饮酒者(AOR，1.79；95%CI，1.06-3.04 vs.AOR，2.43；95%CI，1.45-4.06)。问题饮酒者也更有可能从事多种类型的高危性行为，并有包括HSV-2在内的其他STD感染。结论：旨在限制饮酒或促进戒酒的计划可能有助于减少该人群的高危行为，减轻HIV/STD的负担。
Objectives: To examine the relationship between patterns of alcohol use and HIV infection and to assess the association between problem drinking and the prevalence of risk factors for HIV among a sample of high-risk African women.Methods: Baseline data were collected between 2002 and 2003 during enrollment of 1050 women in a prospective cohort study designed to assess risk factors for HIV. Information about demographic and employment characteristics, sexual behaviors, and drinking patterns were obtained by interviews. The CAGE questionnaire was used to assess problem drinking. The association between measures of alcohol use and HIV/STDs and sexual behaviors were summarized using odds ratios, adjusted odds ratios (AOR), and 95% confidence intervals (CI).Results: HIV prevalence was 19.0% (95% CI, 16.6%-21.4%). Overall 73.9% of the women drank alcohol whereas 34.6% were classified as problem drinkers. After adjusting for demographic and employment variables, drinkers were at increased risk to be HIV+ when compared with nondrinkers (AOR, 2.10; 95% CI, 1.29-3.42). Greater involvement with alcohol, as indicated by recency, frequency and quantity consumed, was associated with increased risk. Problem drinkers were at greater risk to be HIV+ than nonproblem drinkers (AOR, 1.79; 95% CI, 1.06-3.04 vs. AOR, 2.43; 95% CI, 1.45-4.06). Problem drinkers were also more likely to have engaged in several types of high-risk sexual behaviors and to have other STD infections including HSV-2.Conclusion: Programs aiming at limiting alcohol use or promoting abstinence from alcohol might help to reduce high-risk behaviors and lower the burden of HIV/STDs in this population.