Multiple sequence alignment with the Clustal series of programs
Multiple sequence alignment with the Clustal series of programs
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DOI：
10.1093/nar/gkg500
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发表时间：
2003-07-01
影响因子：
14.9
通讯作者：
Thompson, JD
中科院分区：
文献类型：
--
作者：
Chenna, R;Sugawara, H;Thompson, JD
Clustal系列程序广泛用于分子生物学中核酸和蛋白质序列的多重比对以及系统发育树的制备。这些程序的受欢迎程度取决于许多因素，不仅包括结果的准确性，还包括程序的鲁棒性、可移植性和用户友好性。新功能包括NEXUS和FASTA格式输出，打印范围编号和更快的树计算。虽然Clustal最初是为了在本地计算机上运行而开发的，但已经建立了许多网络服务器，特别是在EBI（欧洲生物信息学研究所）（http：//www.ebi.ac.uk/clustalw/）。
The Clustal series of programs are widely used in molecular biology for the multiple alignment of both nucleic acid and protein sequences and for preparing phylogenetic trees. The popularity of the programs depends on a number of factors, including not only the accuracy of the results, but also the robustness, portability and user-friendliness of the programs. New features include NEXUS and FASTA format output, printing range numbers and faster tree calculation. Although, Clustal was originally developed to run on a local computer, numerous Web servers have been set up, notably at the EBI (European Bioinformatics Institute) (http://www.ebi.ac.uk/clustalw/).